US 12,275,719 B2
Small molecule inhibitors of galectin-3
Chunjian Liu, Pennington, NJ (US); David S. Yoon, Ambler, PA (US); Wei Wang, Princeton, NJ (US); Jianxin Feng, Bensalem, PA (US); Bruce A. Ellsworth, Princeton, NJ (US); and Alicia Regueiro-Ren, New Hope, PA (US)
Assigned to Bristol-Myers Squibb Company, Princeton, NJ (US)
Appl. No. 17/439,845
Filed by BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US)
PCT Filed Mar. 25, 2020, PCT No. PCT/US2020/024548
§ 371(c)(1), (2) Date Sep. 16, 2021,
PCT Pub. No. WO2020/198266, PCT Pub. Date Oct. 1, 2020.
Claims priority of provisional application 62/823,684, filed on Mar. 26, 2019.
Prior Publication US 2022/0185800 A1, Jun. 16, 2022
Int. Cl. C07H 17/02 (2006.01); C07D 405/14 (2006.01); C07D 417/14 (2006.01); C07H 19/056 (2006.01)
CPC C07D 405/14 (2013.01) [C07D 417/14 (2013.01); C07H 17/02 (2013.01); C07H 19/056 (2013.01)] 4 Claims
 
1. A compound selected from:

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.