US 12,274,983 B2
Membrane structure body having matrix structure and biomolecule filter using same
Kyu Nam Kim, Suwon Si (KR); and Sunghoon Kim, Suwon (KR)
Assigned to Metapore Co., Ltd., (KR)
Appl. No. 16/964,855
Filed by METAPORE CO., LTD, Suwon-si (KR)
PCT Filed Jan. 25, 2019, PCT No. PCT/KR2019/001102
§ 371(c)(1), (2) Date Feb. 22, 2021,
PCT Pub. No. WO2019/147071, PCT Pub. Date Aug. 1, 2019.
Claims priority of application No. 1020180010006 (KR), filed on Jan. 26, 2018; and application No. 2019001102 (KR), filed on Jan. 25, 2019.
Prior Publication US 2021/0162348 A1, Jun. 3, 2021
Int. Cl. B01D 63/08 (2006.01); B01D 61/14 (2006.01); B01D 61/18 (2006.01); G01N 1/34 (2006.01); G01N 1/40 (2006.01)
CPC B01D 63/087 (2013.01) [B01D 61/147 (2013.01); B01D 61/18 (2013.01); G01N 1/34 (2013.01); G01N 1/4077 (2013.01); B01D 2313/086 (2013.01); B01D 2313/16 (2013.01); G01N 2001/4088 (2013.01)] 12 Claims
OG exemplary drawing
 
1. A membrane structure for filtering a sample comprising a plurality of biomolecules of varying sizes, the membrane structure comprising:
a filtering part having a first surface and a second surface opposite to the first surface the filtering part comprising a plurality of window regions spaced apart by a blocking region interposing each window region of the plurality of window regions, each window region of the plurality of window regions having a plurality of window cells arranged in a matrix configuration defining a flow path along the first surface, the flow path including a flow path end, each window region having a plurality of micro-holes, each micro-hole of the plurality of micro-holes having a substantially equal predetermined size, the plurality of window regions being configured to enable biomolecules within the sample having up to a predetermined size to pass from the first surface to the second surface and to retain biomolecules having a size larger than the predetermined size on the first surface as the sample flows along said flow path thereby enabling a size-based separation of biomolecules along the plurality of window regions; and
a support part extending from the filtering part so as to support the filtering part; and
a membrane structure outlet disposed at the flow path end and configured to receive the biomolecules having up to the predetermined size.