US 12,274,865 B2
Devices and methods for precision dose delivery
Trevor Langley, Rensselaer, NY (US); Justin Bechstein, Philadelphia, PA (US); Jeremy Odegard, Hudson, WI (US); Sibgat Ulla, Rensselaer, NY (US); Daniel Halbig, Rensselaer, NY (US); Bryan Grygus, Clifton Park, NY (US); Prithvi Singh, Rensselaer, NY (US); Andrew Dumont, Rensselaer, NY (US); David Nett, Rensselaer, NY (US); Tasha Gillum, Rensselaer, NY (US); and Ryan Ainsworth, Rensselaer, NY (US)
Assigned to Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US)
Filed by Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US)
Filed on Aug. 1, 2022, as Appl. No. 17/816,615.
Application 17/816,615 is a continuation of application No. 17/457,526, filed on Dec. 3, 2021.
Application 17/816,615 is a continuation of application No. 17/354,850, filed on Jun. 22, 2021, granted, now 11,439,758.
Application 17/457,526 is a continuation of application No. PCT/US2020/036200, filed on Jun. 4, 2020.
Application 17/457,526 is a continuation of application No. PCT/US2020/036200, filed on Jun. 4, 2020.
Claims priority of provisional application 62/860,481, filed on Jun. 12, 2019.
Claims priority of provisional application 62/857,678, filed on Jun. 5, 2019.
Prior Publication US 2022/0370721 A1, Nov. 24, 2022
Int. Cl. A61M 5/315 (2006.01); A61M 5/31 (2006.01); A61F 9/00 (2006.01)
CPC A61M 5/31505 (2013.01) [A61M 5/3135 (2013.01); A61M 5/3146 (2013.01); A61M 5/31536 (2013.01); A61M 5/31583 (2013.01); A61F 9/0008 (2013.01); A61M 2005/3139 (2013.01); A61M 2005/31508 (2013.01); A61M 2005/3154 (2013.01); A61M 2205/584 (2013.01)] 25 Claims
OG exemplary drawing
 
1. A drug delivery device, comprising:
a body;
a flange coupled to the body, the flange including a channel defined by an interior surface and a groove formed in the interior surface; and
a plunger rod coupled to the flange, the plunger rod including a proximal end and an extension extending distally from the proximal end;
wherein the extension is configured to compress radially-inwards and engage the interior surface as the plunger rod moves relative to the flange by a first stroke, the groove is configured to receive the extension and the extension is configured to expand radially-outwards as the plunger rod rotates relative to the flange, and the extension is configured to engage the groove of the flange as the plunger rod moves relative to the flange by a second stroke.