US 12,274,786 B2
Surface treatment of contact lens and treatment of ocular discomfort by water soluble polymers and lipids/liposomes
Jacob Klein, Rehovot (IL); Ronit Goldberg, Rehovot (IL); and Jasmine Seror, Rehovot (IL)
Assigned to Yeda Research and Development Co. Ltd., Rehovot (IL)
Filed by Yeda Research and Development Co. Ltd., Rehovot (IL)
Filed on Aug. 19, 2021, as Appl. No. 17/406,168.
Application 17/406,168 is a division of application No. 15/319,014, granted, now 11,883,533, previously published as PCT/IL2015/050605, filed on Jun. 15, 2015.
Claims priority of provisional application 62/012,379, filed on Jun. 15, 2014.
Prior Publication US 2021/0378960 A1, Dec. 9, 2021
Int. Cl. A61K 9/127 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 31/728 (2006.01); A61K 31/77 (2006.01); A61K 31/79 (2006.01); A61K 47/10 (2017.01); A61K 47/32 (2006.01); A61K 47/36 (2006.01); B65D 35/00 (2006.01); B65D 75/36 (2006.01)
CPC A61K 9/127 (2013.01) [A61K 9/0048 (2013.01); A61K 9/08 (2013.01); A61K 31/728 (2013.01); A61K 31/77 (2013.01); A61K 31/79 (2013.01); A61K 47/10 (2013.01); A61K 47/32 (2013.01); A61K 47/36 (2013.01); B65D 35/00 (2013.01); B65D 75/36 (2013.01)] 11 Claims
 
1. A method of reducing a friction coefficient of a surface of a contact lens, the method comprising rinsing and/or immersing the contact lens in a solution comprising at least one water-soluble polymer, liposomes, and an aqueous carrier, wherein said at least one water-soluble polymer comprises a non-ionic polymer, and an average molecular weight of said at least one water-soluble polymer is in a range of from 3 kDa to 10 MDa, and wherein a concentration of phospholipids of said liposomes in the solution is in a range of from 0.5 mM to 500 mM.