US 12,274,781 B2
Use of enzyme-modified isoquercitrin
Hiroyuki Sato, Toyonaka (JP); Makoto Nakauma, Toyonaka (JP); Akira Ikegami, Toyonaka (JP); Takahiro Funami, Toyonaka (JP); and Hideyuki Orikoshi, Toyonaka (JP)
Assigned to SAN-EI GEN F.F.I., INC., Osaka (JP)
Filed by SAN-EI GEN F.F.I., INC., Toyonaka (JP)
Filed on Sep. 23, 2020, as Appl. No. 17/029,444.
Application 17/029,444 is a division of application No. 15/780,828, abandoned, previously published as PCT/JP2016/085980, filed on Dec. 2, 2016.
Claims priority of application No. 2015-237874 (JP), filed on Dec. 4, 2015; and application No. 2015-237878 (JP), filed on Dec. 4, 2015.
Prior Publication US 2021/0007980 A1, Jan. 14, 2021
Int. Cl. A61K 9/00 (2006.01); A23L 33/10 (2016.01); A61K 8/73 (2006.01); A61K 31/7048 (2006.01); A61K 47/36 (2006.01); A61P 1/02 (2006.01); A61Q 11/00 (2006.01)
CPC A61K 9/0056 (2013.01) [A23L 33/10 (2016.08); A61K 8/73 (2013.01); A61K 31/7048 (2013.01); A61K 47/36 (2013.01); A61P 1/02 (2018.01); A61Q 11/00 (2013.01)] 11 Claims
 
1. A method of promoting salivation in a person with reduced salivation function, the method comprising applying a salivator to the oral cavity of the person or allowing the person to orally ingest the salivator,
wherein the salivator comprises an enzymatically modified isoquercitrin in an effective amount to provide a salivation-promoting effect, and a thickening polysaccharide,
the enzymatically modified isoquercitrin contains as a main component a mixture of two or more a-glucosyl isoquercitrins represented by the following formula:

OG Complex Work Unit Chemistry
wherein n represents an integer of 0 to 10, and
the effective amount is 0.001 to 0.5 mass % in terms of a-glucosyl isoquercitrin.