US 12,274,773 B2
Cosmetic compositions and methods of use
Kristina Trujillo, Placitas, NM (US); and Katie Uilk, Albuquerque, NM (US)
Assigned to K&K BIOTECH, Albuquerque, NM (US)
Filed by K&K BIOTECH, Albuquerque, NM (US)
Filed on Sep. 3, 2020, as Appl. No. 17/011,217.
Application 17/011,217 is a continuation of application No. PCT/US2019/063602, filed on Nov. 27, 2019.
Claims priority of provisional application 62/772,856, filed on Nov. 29, 2018.
Prior Publication US 2020/0397676 A1, Dec. 24, 2020
Int. Cl. A61K 8/34 (2006.01); A61K 8/31 (2006.01); A61K 8/35 (2006.01); A61K 8/40 (2006.01); A61K 8/41 (2006.01); A61K 8/81 (2006.01); A61K 8/92 (2006.01); A61K 8/97 (2017.01); A61K 31/055 (2006.01); A61K 31/06 (2006.01); A61K 36/889 (2006.01); A61K 38/00 (2006.01); A61P 17/02 (2006.01); A61Q 19/08 (2006.01)
CPC A61K 8/347 (2013.01) [A61K 8/315 (2013.01); A61K 8/35 (2013.01); A61K 8/40 (2013.01); A61K 8/418 (2013.01); A61K 8/8194 (2013.01); A61K 8/922 (2013.01); A61K 8/97 (2013.01); A61K 31/055 (2013.01); A61K 31/06 (2013.01); A61K 36/889 (2013.01); A61K 38/005 (2013.01); A61P 17/02 (2018.01); A61Q 19/08 (2013.01); A61K 2800/591 (2013.01); A61K 2800/782 (2013.01); A61K 2800/805 (2013.01)] 17 Claims
 
1. A method of treating a cosmetic condition of the keratinous tissue of a subject comprising administering to the subject a composition comprising an effective amount of at least one compound which exhibits dual activity as a NF-KB signaling inhibitor and a Nrf2 signaling agonist, in combination with at least one cosmetic additive, wherein the compound comprises at least one structure selected from the group consisting of:
stilbene which contains at least one substitute on at least one of the aryl rings; dienone; and
3-hydroxy-1,3-diphenylprop-2-en-1-one,
wherein the cosmetic condition of the keratinous tissue of the subject comprises at least one condition selected from the group consisting of acne scars, stretch marks, and wrinkles.