US 12,274,759 B2
Affibody proteins specific for B7-H3 (CD276)
Lotfi Abou-Elkacem, Houston, TX (US); Juergen Karl Willmann, Stanford, CA (US); Benjamin J. Hackel, Edina, MN (US); Lawrence Arthur Stern, Monrovia, CA (US); Patrick Samuel Lown, Minneapolis, MN (US); Amelie Margarete Marianne Lutz, Stanford, CA (US); and Rakesh Kumar Bam, Menlo Park, CA (US)
Assigned to REGENTS OF THE UNIVERSITY OF MINNESOTA, Minneapolis, MN (US)
Appl. No. 17/267,733
Filed by THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, Stanford, CA (US); and REGENTS OF THE UNIVERSITY OF MINNESOTA, Minneapolis, MN (US)
PCT Filed Aug. 22, 2019, PCT No. PCT/US2019/047764
§ 371(c)(1), (2) Date Feb. 10, 2021,
PCT Pub. No. WO2020/041626, PCT Pub. Date Feb. 27, 2020.
Claims priority of provisional application 62/872,122, filed on Jul. 9, 2019.
Claims priority of provisional application 62/721,974, filed on Aug. 23, 2018.
Prior Publication US 2021/0340257 A1, Nov. 4, 2021
Int. Cl. A61K 38/16 (2006.01); A61K 9/00 (2006.01); A61K 47/68 (2017.01); A61K 49/22 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01)
CPC A61K 49/221 (2013.01) [A61K 9/0019 (2013.01); A61K 47/6849 (2017.08); A61K 49/223 (2013.01); A61P 35/00 (2018.01); C07K 16/2827 (2013.01); A61K 2039/505 (2013.01); C07K 2317/92 (2013.01); C07K 2318/20 (2013.01)] 26 Claims
 
1. A polypeptide comprising residues1-36 of any one of SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, or SEQ ID NO:4.