US 12,274,679 B2
Substituted alkylphenols as HCN1 antagonists
Gareth R. Tibbs, Staten Island, NY (US); Peter A. Goldstein, Hartsdale, NY (US); Anthony A. Sauve, New Rochelle, NY (US); Rajendra Uprety, Cary, NC (US); James David Warren, Jr., New York, NY (US); Rebecca L. Joyce, Newark, NJ (US); and Dipti N. Barman, Rutherford, NJ (US)
Assigned to Cornell University, Ithaca, NY (US)
Filed by Cornell University, Ithaca, NY (US)
Filed on Apr. 26, 2023, as Appl. No. 18/307,174.
Application 18/307,174 is a division of application No. 17/254,787, granted, now 11,684,590, previously published as PCT/US2019/039493, filed on Jun. 27, 2019.
Claims priority of provisional application 62/803,109, filed on Feb. 8, 2019.
Claims priority of provisional application 62/690,778, filed on Jun. 27, 2018.
Prior Publication US 2024/0366529 A1, Nov. 7, 2024
Int. Cl. A61K 31/11 (2006.01); A61K 31/20 (2006.01); A61K 31/336 (2006.01); A61K 31/4015 (2006.01); A61K 47/64 (2017.01); A61P 25/04 (2006.01)
CPC A61K 31/11 (2013.01) [A61K 31/20 (2013.01); A61K 31/336 (2013.01); A61K 31/4015 (2013.01); A61K 47/643 (2017.08); A61P 25/04 (2018.01)] 10 Claims
 
1. A method of treating pain in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound of formula:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.