US 12,274,532 B2
Lumen morphology and vascular resistance measurements data collection systems apparatus and methods
Joseph M. Schmitt, Andover, MA (US); Joel M. Friedman, Andover, MA (US); Christopher Petroff, Groton, MA (US); and Amr Elbasiony, Chelmsford, MA (US)
Assigned to LightLab Imaging, Inc., Westford, MA (US)
Filed by LightLab Imaging, Inc., Westford, MA (US)
Filed on Oct. 21, 2021, as Appl. No. 17/507,259.
Application 17/507,259 is a continuation of application No. 16/549,814, filed on Aug. 23, 2019.
Application 16/549,814 is a continuation of application No. 13/796,710, filed on Mar. 12, 2013.
Application 13/796,710 is a continuation of application No. 12/888,347, filed on Sep. 22, 2010, granted, now 9,138,147, issued on Sep. 22, 2015.
Claims priority of provisional application 61/334,834, filed on May 14, 2010.
Claims priority of provisional application 61/244,992, filed on Sep. 23, 2009.
Prior Publication US 2022/0095932 A1, Mar. 31, 2022
Int. Cl. A61B 5/02 (2006.01); A61B 5/00 (2006.01)
CPC A61B 5/02007 (2013.01) [A61B 5/0066 (2013.01); A61B 5/0073 (2013.01); A61B 5/0084 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A method for determining the severity of a stenotic lesion comprising:
generating, by one or more processors, a 3D model of a vessel that is based on vessel image data taken from a patient;
identifying, by the one or more processors, a stenotic lesion within the vessel;
generating, by the one or more processors, a patient-specific blood flow or resistance model of the vessel based on the vessel image data taken from the patient;
calculating, by the one or more processors, one or more vessel blood flow or resistance values in a region of the stenotic lesion, wherein at least one of the one or more vessel blood flow or resistance values are based on the patient-specific blood flow or resistance model simulating a hyperemic condition within the patient without physically inducing a hyperemic condition, and wherein the patient-specific blood flow or resistance model incorporates hyperemic microvascular resistance of branch vessels from the vessel;
providing for display the one or more vessel blood flow or resistance values in relation to a representation of the vessel.