US 12,274,484 B2
Cryosurgical device and materials and method of use thereof
Martin J. Moskovitz, West Orange, NJ (US)
Filed by Martin J. Moskovitz, West Orange, NJ (US)
Filed on Apr. 22, 2024, as Appl. No. 18/641,540.
Application 18/641,540 is a continuation in part of application No. PCT/US2023/062017, filed on Feb. 6, 2023.
Claims priority of provisional application 63/346,504, filed on May 27, 2022.
Claims priority of provisional application 63/307,359, filed on Feb. 7, 2022.
Prior Publication US 2024/0277394 A1, Aug. 22, 2024
Int. Cl. A61B 18/02 (2006.01); A61B 18/00 (2006.01)
CPC A61B 18/02 (2013.01) [A61B 2018/00464 (2013.01); A61B 2018/00714 (2013.01); A61B 2018/0293 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A method of causing ice phase-change lipolysis in a mammalian subject, the method comprising subcutaneously injecting a slurry of chilled aqueous solution and ice such that the slurry comes into proximity with fat cells to be ice-phase-lipolysed, wherein the injecting is performed using an injection device comprising:
a sterile, single-use funnel-shaped container configured to receive and contain a slurry and comprising a lid for sealing the container;
a mixing means coupled to the container comprising
one or more mixing tubes, wherein each end of each mixing tube is attached to the container, and wherein one end of each mixing tube is attached to the container at a lower end thereof, and
one or more mixing pumps associated with each mixing tube and configured to circulate the slurry from the container through each mixing tube to agitate the slurry, and wherein one or more mixing pumps is a peristaltic pump;
a patient tube operably coupled to the container;
a roller pump operably coupled to the container to facilitate administering the slurry from the container to a patient via the patient tube, and wherein the roller pump is a peristaltic roller pump;
a cannula or an instillation needle operably coupled to the roller pump via the patient tube to introduce the slurry to a patient; and
wherein the mixing means is configured to agitate the slurry, thereby maintaining a predetermined liquid-ice ratio and/or consistency.