US 12,274,276 B2
Dissolvable-chewable tablet
Feng Gao, Midlothian, VA (US); Diane L. Gee, Chesterfield, VA (US); Phillip M. Hulan, Midlothian, VA (US); Shuzhong Zhuang, Glen Allen, VA (US); William J. Burke, Nashville, TN (US); and Gerd Kobal, Sandy Hook, VA (US)
Assigned to Altria Client Services LLC, Richmond, VA (US)
Filed by ALTRIA CLIENT SERVICES LLC, Richmond, VA (US)
Filed on Oct. 3, 2014, as Appl. No. 14/505,965.
Claims priority of provisional application 61/886,358, filed on Oct. 3, 2013.
Prior Publication US 2015/0098978 A1, Apr. 9, 2015
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/5415 (2006.01); A23G 3/40 (2006.01); A23G 3/42 (2006.01); A23G 3/54 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 31/196 (2006.01); A61K 31/21 (2006.01); A61K 31/4402 (2006.01); A61K 31/4468 (2006.01); A61K 31/485 (2006.01); A61K 31/513 (2006.01); A61K 31/522 (2006.01); A61K 31/53 (2006.01); A61K 31/55 (2006.01); A61K 31/565 (2006.01); A61K 31/568 (2006.01); A61K 31/57 (2006.01); A61K 31/706 (2006.01); A61K 45/06 (2006.01)
CPC A23G 3/54 (2013.01) [A23G 3/40 (2013.01); A23G 3/42 (2013.01); A61K 9/0056 (2013.01); A61K 9/2018 (2013.01); A61K 9/205 (2013.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); A61K 9/2072 (2013.01); A61K 9/2095 (2013.01); A61K 31/196 (2013.01); A61K 31/21 (2013.01); A61K 31/4402 (2013.01); A61K 31/4468 (2013.01); A61K 31/485 (2013.01); A61K 31/513 (2013.01); A61K 31/522 (2013.01); A61K 31/53 (2013.01); A61K 31/5415 (2013.01); A61K 31/55 (2013.01); A61K 31/565 (2013.01); A61K 31/568 (2013.01); A61K 31/57 (2013.01); A61K 31/706 (2013.01); A61K 45/06 (2013.01)] 28 Claims
 
1. A dissolvable-chewable tablet comprising:
a single and continuous phase including
a solid solution having a glass transition temperature ranging from about −75° C. to about 40° C., the solid solution including,
soluble fibers including maltodextrin, the dissolvable-chewable tablet including greater than or equal to about 55 weight percent of the soluble fibers, and
a sugar alcohol, the dissolvable-chewable tablet including greater than or equal to about 20 weight percent to less than or equal to about 30 weight percent of the sugar alcohol, the sugar alcohol including erythritol, isomalt, hydrogenated starch hydrolysates, or any combination thereof;
an oil dispersed in the solid solution, the oil including palm kernel oil, coconut oil, corn oil, cotton seed oil, olive oil, peanut oil, canola oil, sesame oil, soybean oil, rapeseed oil, safflower oil, sunflower oil, mustard oil, almond oil, beech nut oil, cashew oil, hazelnut oil, macadamia oil, pecan oil, pine nut oil, pistachio oil, walnut oil, pumpkin oil, watermelon seed oil, oils from melons and gourd seeds, flaxseed oil, cocoa butter, or any combination thereof;
cellulosic fibers dispersed in the solid solution, the dissolvable-chewable tablet including greater than or equal to about 20 weight percent to less than or equal to about 40 weight percent of the cellulosic fibers;
an additive dispersed or dissolved in the solid solution, the additive including buprenorphin, nitroglycerin, diclofenac, fentanyl, carbamazepine, galantamine, acyclovir, polyamidoamine nanoparticles, testosterone, estradiol, progesterone, calcitonin, fluorouracil, naltrexone, odansetron, decitabine, selegiline, lamotrigine, prochlorperazine, or any combination thereof; and
a mouth-soluble coating covering at least a portion of the single and continuous phase, the mouth-soluble coating including carnauba Carnuba wax, miglycol, titanium dioxide, kaolin kaoline, bentonite, or any combination thereof,
the dissolvable-chewable tablet having a longest dimension greater than or equal to about 1 millimeter to less than or equal to about 25 millimeters.