US 11,954,888 B2
Device, microscope device, method, and program
Hiroaki Kii, Kawasaki (JP); and Shinichi Takayama, Tokyo (JP)
Assigned to NIKON CORPORATION, Tokyo (JP)
Filed by NIKON CORPORATION, Tokyo (JP)
Filed on Dec. 22, 2020, as Appl. No. 17/130,294.
Application 17/130,294 is a continuation of application No. PCT/JP2018/024676, filed on Jun. 28, 2018.
Prior Publication US 2021/0125335 A1, Apr. 29, 2021
Int. Cl. G06T 7/90 (2017.01); G06T 7/00 (2017.01); G06V 10/56 (2022.01); G06V 20/69 (2022.01); G02B 21/36 (2006.01)
CPC G06T 7/90 (2017.01) [G06T 7/0012 (2013.01); G06V 10/56 (2022.01); G06V 20/695 (2022.01); G06V 20/698 (2022.01); G02B 21/365 (2013.01); G06T 2207/10024 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/30024 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A cell state evaluation device comprising:
a processor;
a memory encoded with instructions executed by the processor, the instructions causing the processor to perform operations comprising:
calculating color information of at least one or a combination of hue, saturation, or lightness in the color space of an image of one captured cell or a plurality of captured cells in a captured image;
determining a cultured state of the cell on the basis of the color information and color reference information;
storing a positive region set on the basis of the color information of the image of one sample cell or a plurality of sample cells in the color space as the color reference information which is the determination standard; and
obtaining a positive rate which is a proportion of color information included in the positive region and served as color measurement targets on the basis of the color information and the positive region,
wherein the positive region is a color region in the color space into which the one sample cell or a plurality of sample cells change as growth progresses to the differentiation induction process of the cell maturation process, and
wherein the determining includes determining the growth process of the one captured cell or a plurality of captured cells in the cultured state on the basis of the positive rate.