	US 11,952,615 B2
	Nucleic acid control molecules from non-human organisms
Hatim T. Allawi, Middleton, WI (US); Graham P. Lidgard, Middleton, WI (US); Brian Aizenstein, Madison, WI (US); and Melissa M. Gray, Madison, WI (US)
Assigned to Exact Sciences Corporation, Madison, WI (US)
Filed by Exact Sciences Corporation, Madison, WI (US)
Filed on Nov. 18, 2021, as Appl. No. 17/529,896.
Application 17/529,896 is a division of application No. 16/318,578, granted, now 11,208,680, previously published as PCT/US2017/042842, filed on Jul. 19, 2017.
Claims priority of provisional application 62/364,049, filed on Jul. 19, 2016.
Prior Publication US 2022/0136035 A1, May 5, 2022
Int. Cl. C12Q 1/6806 (2018.01); C12N 15/10 (2006.01)

CPC C12Q 1/6806 (2013.01) [C12N 15/1006 (2013.01); C12Q 2600/154 (2013.01); C12Q 2600/16 (2013.01)]

19 Claims

1. A kit for analyzing methylated DNA from a biological sample from a human, the kit comprising:

a) synthetic methylated DNA comprising a zebrafish DNA nucleotide sequence;

b) an oligonucleotide comprising a region complementary to said synthetic methylated DNA;

c) an oligonucleotide comprising a region complementary to methylated DNA from a human; and

d) a methylation-specific reagent system.