	US 11,952,608 B2
	Methods for production of oxygenated terpenes
Ajikumar Parayil Kumaran, Watertown, MA (US); Chin Giaw Lim, Cambridge, MA (US); Liwei Li, Cambridge, MA (US); Souvik Ghosh, Cambridge, MA (US); Christopher Pirie, Cambridge, MA (US); and Anthony Qualley, Cambridge, MA (US)
Assigned to Manus Bio Inc., Cambridge, MA (US)
Filed by Manus Bio Inc., Cambridge, MA (US)
Filed on Jan. 5, 2021, as Appl. No. 17/141,758.
Application 17/141,758 is a continuation of application No. 15/505,503, granted, now 10,934,564, previously published as PCT/US2015/046369, filed on Aug. 21, 2015.
Claims priority of provisional application 62/040,284, filed on Aug. 21, 2014.
Prior Publication US 2021/0292798 A1, Sep. 23, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C12N 9/02 (2006.01); A01N 27/00 (2006.01); A23L 27/12 (2016.01); C12P 5/00 (2006.01); C12P 7/26 (2006.01)

CPC C12P 7/26 (2013.01) [A01N 27/00 (2013.01); A23L 27/13 (2016.08); C12N 9/0073 (2013.01); C12P 5/002 (2013.01); C12Y 114/13078 (2013.01); A23V 2002/00 (2013.01); C07K 2319/03 (2013.01)]

5 Claims

1. A sesquiterpene oxidase comprising an amino acid sequence that has at least 80% sequence identity to the amino acid sequence SEQ ID NO: 37 or SEQ ID NO: 38, wherein the amino acid sequence of the sesquiterpene oxidase comprises a T499N substitution, and wherein the amino acid numbering corresponds to the amino acid sequence of SEQ ID NO: 37.