US 11,952,607 B2
Microorganisms and methods for improved biological production of ethylene glycol
Zachary Robert Cowden, San Diego, CA (US); Ching Leang, Evanston, IL (US); Michael Koepke, Chicago, IL (US); Rasmus Overgaard Jensen, Evanston, IL (US); and Alexander Paul Mueller, Skokie, IL (US)
Assigned to LanzaTech, Inc., Skokie, IL (US)
Filed by LanzaTech, Inc., Skokie, IL (US)
Filed on Aug. 5, 2022, as Appl. No. 17/817,766.
Claims priority of provisional application 63/261,185, filed on Sep. 14, 2021.
Claims priority of provisional application 63/260,054, filed on Aug. 6, 2021.
Prior Publication US 2023/0065430 A1, Mar. 2, 2023
Int. Cl. C12N 15/74 (2006.01); C12N 1/20 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 9/88 (2006.01); C12N 15/52 (2006.01); C12P 7/18 (2006.01); C12R 1/145 (2006.01)
CPC C12P 7/18 (2013.01) [C12N 1/20 (2013.01); C12N 9/0008 (2013.01); C12N 9/1025 (2013.01); C12N 9/1096 (2013.01); C12N 9/88 (2013.01); C12N 15/52 (2013.01); C12R 2001/145 (2021.05); C12Y 102/01003 (2013.01); C12Y 102/01021 (2013.01); C12Y 203/03001 (2013.01); C12Y 206/01044 (2013.01); C12Y 401/03001 (2013.01)] 20 Claims
 
1. A genetically engineered C1-fixing microorganism capable of producing ethylene glycol or a precursor of ethylene glycol from a gaseous substrate comprising: a disruptive mutation in a gene encoding diol dehydratase.