US 11,952,566 B2
Overpressure protection means
Bernhard Diel, Dransfeld (DE); Andreas Klemm, Kassel (DE); Matthias Hielscher, Hessisch Lichtenau (DE); Alexandre Espachs, Göttingen (DE); and André Grebe, Malsfeld (DE)
Assigned to Sartorius Stedim Biotech GmbH, Göttingen (DE)
Appl. No. 17/052,942
Filed by Sartorius Stedim Biotech GmbH, Göttingen (DE)
PCT Filed Jan. 4, 2019, PCT No. PCT/EP2019/050128
§ 371(c)(1), (2) Date Nov. 4, 2020,
PCT Pub. No. WO2019/211006, PCT Pub. Date Nov. 7, 2019.
Claims priority of application No. 10 2018 003 676.7 (DE), filed on May 4, 2018.
Prior Publication US 2021/0238533 A1, Aug. 5, 2021
Int. Cl. C12M 3/00 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01); C12M 1/36 (2006.01)
CPC C12M 41/40 (2013.01) [C12M 23/28 (2013.01); C12M 23/40 (2013.01); C12M 23/58 (2013.01); C12M 41/48 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A system comprising:
a bioprocess device comprising:
at least one disposable container which is configured to at least partially receive at least one medium; and
at least one overpressure protection means which is connected to the at least one disposable container in fluid terms, wherein the at least one overpressure protection means is configured, in the event of an activation, to guide the at least one medium at least partially
into a device region which is arranged upstream of the overpressure protection means with respect to a flow direction, and/or
into the at least one disposable container; and/or
into at least one additional second container;
a main line for fluid connection of the at least one disposable container to a target container; and
at least one of:
at least one discharge which is configured, when the at least one overpressure protection means is activated, to direct the at least one medium at least partially into at least one additional container; or
a bypass line which is configured, when the at least one overpressure protection means is activated, to direct the at least one medium at least partially back into the device region which is arranged upstream of the overpressure protection means with respect to a flow direction, including into a portion of the main line and/or into the at least one disposable container,
wherein the at least one overpressure protection means is arranged on the discharge and/or the bypass line and, when the at least one overpressure protection means is activated, the discharge and/or the bypass line is/are connected in fluid terms to the main line; and
at least one pressure-producing means, including a pump, wherein the at least one pressure-producing means is configured to pump at least a portion of the at least one medium from the at least one disposable container into the third container in the flow direction,
wherein the at least one pressure-producing means is arranged in fluid communication with the disposable container and is configured to produce a pressure drop within the disposable container and/or along the main line.