US 11,952,429 B2
Recombinant monoclonal antibodies and corresponding antigens for colon and pancreatic cancers
J. Andrew Bristol, Rockville, MD (US); and Judith A. Kantor, Glenshaw, PA (US)
Assigned to PRECISION BIOLOGICS, INC.
Filed by PRECISION BIOLOGICS, INC., Bethesda, MD (US)
Filed on Jun. 24, 2022, as Appl. No. 17/848,694.
Application 17/848,694 is a division of application No. 16/796,572, filed on Feb. 20, 2020, granted, now 11,401,341.
Application 16/796,572 is a division of application No. 16/009,497, filed on Jun. 15, 2018, abandoned.
Application 16/009,497 is a division of application No. 15/158,638, filed on May 19, 2016, granted, now 10,023,650, issued on Jul. 17, 2018.
Application 15/158,638 is a division of application No. 14/308,851, filed on Jun. 19, 2014, granted, now 9,371,375, issued on Jun. 21, 2016.
Application 14/308,851 is a division of application No. 13/012,706, filed on Jan. 24, 2011, granted, now 8,802,090, issued on Aug. 12, 2014.
Application 13/012,706 is a division of application No. 12/859,526, filed on Aug. 19, 2010, granted, now 8,524,456, issued on Sep. 3, 2013.
Application 12/859,526 is a division of application No. 12/266,889, filed on Nov. 7, 2008, granted, now 7,829,678, issued on Nov. 9, 2010.
Claims priority of provisional application 60/996,255, filed on Nov. 8, 2007.
Prior Publication US 2022/0403045 A1, Dec. 22, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 45/06 (2006.01); A61K 39/395 (2006.01); A61K 47/68 (2017.01); C07K 16/18 (2006.01); C07K 16/30 (2006.01); G01N 33/574 (2006.01); G01N 33/577 (2006.01); A61K 39/00 (2006.01)
CPC C07K 16/3046 (2013.01) [A61K 39/39558 (2013.01); A61K 45/06 (2013.01); A61K 47/6859 (2017.08); A61K 47/6863 (2017.08); C07K 16/18 (2013.01); C07K 16/303 (2013.01); G01N 33/57419 (2013.01); G01N 33/57438 (2013.01); G01N 33/577 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/732 (2013.01)] 22 Claims
 
1. An isolated nucleic acid molecule selected from the group consisting of at least one of the following: a nucleic acid molecule with the nucleic acids of SEQ ID NO:12, a nucleic acid molecule with the complementary sequence of SEQ ID NO:12, a nucleic acid molecule with the sequence of SEQ ID NO:13, and the complementary sequence of SEQ ID NO:13.