US 11,952,350 B2
Process for the preparation of fungicidally active strobilurin compounds and intermediates thereof
Prashant Vasant Kini, Mumbai (IN); and Santosh Ganpat Shelke, Mumbai (IN)
Assigned to UPL LTD., Mumbai (IN)
Appl. No. 17/603,430
Filed by UPL LTD, Mumbai (IN)
PCT Filed Apr. 17, 2020, PCT No. PCT/IB2020/053656
§ 371(c)(1), (2) Date Oct. 13, 2021,
PCT Pub. No. WO2020/212928, PCT Pub. Date Oct. 22, 2020.
Claims priority of application No. 201921015651 (IN), filed on Apr. 18, 2019.
Prior Publication US 2022/0194903 A1, Jun. 23, 2022
Int. Cl. C07D 239/52 (2006.01)
CPC C07D 239/52 (2013.01) 19 Claims
 
1. A process for preparation of a compound of Formula (I) comprising:

OG Complex Work Unit Chemistry
reacting a compound of Formula (II) with a compound of Formula (III) in the presence of a 1,5,7-triazabicyclo[4.4.0]dec-5-ene or a salt thereof as a catalyst;

OG Complex Work Unit Chemistry
wherein,
R is selected from halogen and nitrile;
X1 is selected from hydrogen and fluorine;
X2 is chlorine; and
Q is selected from methyl (E)-2-(3-methoxy) acrylate, methyl 2-(3,3-dimethoxy) propanoate, and 5,6-dihydro-1,4,2-dioxazin-3-yl-N-methoxymethanimine.