	US 11,951,206 B2
	Cell housing device
Christopher Thanos, Cumberland, RI (US); Danya M. Lavin, Mansfield, MA (US); Briannan E. Bintz, Lincoln, RI (US); Divya Bhatnagar, Highland Park, NJ (US); John Mills, Warwick, RI (US); and Megan Billings, Warwick, RI (US)
Assigned to Vertex Pharmaceuticals Incorporated, Boston, MA (US)
Appl. No. 16/650,933
Filed by Vertex Pharmaceuticals Incorporated, Boston, MA (US)
PCT Filed Sep. 29, 2018, PCT No. PCT/US2018/053665 § 371(c)(1), (2) Date Mar. 26, 2020, PCT Pub. No. WO2019/068059, PCT Pub. Date Apr. 4, 2019.
Claims priority of provisional application 62/671,297, filed on May 14, 2018.
Claims priority of provisional application 62/565,962, filed on Sep. 29, 2017.
Prior Publication US 2020/0289407 A1, Sep. 17, 2020
Int. Cl. A61K 9/00 (2006.01); A61K 35/39 (2015.01); A61K 47/32 (2006.01); A61K 47/34 (2017.01)

CPC A61K 9/0024 (2013.01) [A61K 35/39 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01)]

30 Claims

1. A cell housing device, comprising:

a first membrane having a first surface, and a second surface opposing the first surface;

a second membrane opposite and attached to the second surface of the first membrane, wherein the first membrane and the second membrane form an enclosed compartment configured to house a cell population, wherein the enclosed compartment includes a plurality of continuous interconnected compartments formed between the first membrane and the second membrane, and wherein at least one of the first membrane and the second membrane is sintered; and

a frame extending at least partially along an outer edge of the first membrane and the second membrane.