US 11,951,073 B2
Device for transferring a liquid from a first vial to a second vial
Maxime Gaillot, Basel (CH); Roberta Leah, Basel (CH); Declan Reilly, Basel (CH); Thomas Thueer, Basel (CH); Jack Carroll, Bristol (GB); James Coop, Bristol (GB); Edward Sims, Bristol (GB); and Mark Teucher, Bath (GB)
Assigned to HOFFMANN-LA ROCHE INC., Little Falls, NJ (US)
Appl. No. 16/760,514
Filed by HOFFMANN-LA ROCHE INC., Little Falls, NJ (US)
PCT Filed Nov. 2, 2018, PCT No. PCT/EP2018/079985
§ 371(c)(1), (2) Date Apr. 30, 2020,
PCT Pub. No. WO2019/086595, PCT Pub. Date May 9, 2019.
Claims priority of application No. 17199752 (EP), filed on Nov. 2, 2017.
Prior Publication US 2021/0196571 A1, Jul. 1, 2021
Int. Cl. A61J 1/20 (2006.01); A61J 1/14 (2023.01)
CPC A61J 1/2048 (2015.05) [A61J 1/1406 (2013.01); A61J 1/2013 (2015.05); A61J 1/2037 (2015.05); A61J 1/2082 (2015.05); A61J 1/2089 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A transfer device for transferring a liquid from a first vial to a second vial, comprising:
a resilient dome portion configured to create an air flow when activated by compression and re-expansion; and
a support body tightly supporting the resilient dome portion to form a chamber comprising air for the air flow, the support body comprising a first vial seat, a second vial seat and a transfer conduit, wherein
the first vial seat of the support body is arranged to receive the first vial,
the second vial seat of the support body is arranged to receive the second vial, and
the transfer conduit comprises end sections each embodied as puncturing members protruding from the first and second vial seats and arranged to establish flow pathways to and/or from an interior of the first vial through a pierceable cover of the first vial and to and/or from an interior of the second vial through a pierceable cover of the second vial, and
wherein when the first vial is received in the first vial seat and the second vial is received in the second vial seat,
one of the puncturing members of the transfer conduit is arranged to end in the pierceable cover of the first vial,
the transfer conduit is arranged to establish a fluid connection between the first vial and the second vial, and
on activation of the resilient dome portion, air is delivered into the first vial by the air flow, creating a pressure rise in the first vial which causes the liquid to transfer from the first vial to the second vial through the transfer conduit,
wherein the transfer conduit comprises a first transfer conduit portion and a second transfer conduit portion,
wherein the first transfer conduit portion is arranged to create a first air flow pathway between the interior of the first vial and the chamber for delivering the air from the chamber into the first vial, when the first vial is received in the first vial seat,
wherein the second transfer conduit portion is arranged to create a second air flow pathway between the interior of the second vial and the chamber for drawing the air from the second vial to the chamber, when the second vial is received in the second vial seat,
wherein the first transfer conduit portion together with the second transfer conduit portion are arranged to create a liquid flow pathway between the interior of the first vial and the interior of the second vial for the liquid being transferred from the first vial to the second vial, when the first vial is received in the first vial seat and the second vial is received in the second vial seat, and
wherein the chamber comprises a bottleneck portion fluidly connected to, and fluidly positioned between, the first transfer conduit portion and the second transfer conduit portion of the transfer conduit, the bottleneck portion being dimensioned for a substantially lossless transfer of the liquid from the first vial via the first transfer conduit portion into the second vial via the second transfer conduit portion.