US 12,272,459 B2
Medical diagnostic apparatus and method for evaluation of pathological conditions using 3D data and images of lamina cribrosa
Kohji Nishida, Osaka (JP); Atsuya Miki, Osaka (JP); Kazuichi Maruyama, Osaka (JP); Ryo Kawasaki, Osaka (JP); Song Mei, Tokyo (JP); Zaixing Mao, Tokyo (JP); Zhenguo Wang, Tokyo (JP); Kinpui Chan, Tokyo (JP); and Xin Sui, Tokyo (JP)
Assigned to Topcon Corporation, Tokyo (JP); and Osaka University, Osaka (JP)
Filed by Topcon Corporation, Tokyo (JP); and Osaka University, Osaka (JP)
Filed on Oct. 5, 2021, as Appl. No. 17/493,856.
Prior Publication US 2023/0105247 A1, Apr. 6, 2023
Int. Cl. G06T 7/12 (2017.01); G06T 7/10 (2017.01); G06T 15/08 (2011.01); G16H 50/20 (2018.01); G16H 50/30 (2018.01)
CPC G16H 50/20 (2018.01) [G06T 7/10 (2017.01); G06T 15/08 (2013.01); G16H 50/30 (2018.01); G06T 2207/10101 (2013.01); G06T 2207/30041 (2013.01)] 19 Claims
OG exemplary drawing
 
19. A non-transitory computer readable storage medium storing instructions, which when executed by a computer, performs steps comprising:
obtaining three-dimensional data of a subject's eye;
separating portions of the three-dimensional data into separate segments;
performing processing differently on each of the separate segments;
combining the separately processed segments to produce a segmented three-dimensional data set;
generating at least one diagnostic metric from the segmented three-dimensional data set;
evaluating a medical condition based on the at least one diagnostic metric; and
identifying a reference plane maximally correlated with a largest surface of a Bruch's Membrane Opening in the subject's eye; and
identifying a smooth polynomial maximally correlated with an anterior surface of a lamina cribrosa in the subject's eye, wherein
the at least one diagnostic metric includes a measurement based on the reference plane.