US 12,269,847 B2
Genetically encoded polypeptide for affinity capture and purification of biologics
Kelli M. Luginbuhl, Durham, NC (US); and Ashutosh Chilkoti, Durham, NC (US)
Assigned to Donaldson Company, Inc., Bloomington, MN (US)
Appl. No. 17/268,314
Filed by Donaldson Company, Inc., Bloomington, MN (US)
PCT Filed Aug. 15, 2019, PCT No. PCT/US2019/046607
§ 371(c)(1), (2) Date Feb. 12, 2021,
PCT Pub. No. WO2020/037100, PCT Pub. Date Feb. 20, 2020.
Claims priority of provisional application 62/764,833, filed on Aug. 16, 2018.
Prior Publication US 2021/0261626 A1, Aug. 26, 2021
Int. Cl. C07K 14/005 (2006.01); C07K 1/14 (2006.01)
CPC C07K 14/005 (2013.01) [C07K 1/145 (2013.01); C07K 2319/705 (2013.01)] 34 Claims
OG exemplary drawing
 
1. A fusion protein comprising at least one capture domain and at least one elastin-like polypeptide (ELP), wherein the at least one capture domain binds to an antibody or fragment thereof.