US 12,269,818 B2
Analogs of xanomeline
Samuel Clark, Miami, FL (US); and Matthew Duncton, Las Vegas, NV (US)
Assigned to Terran Biosciences Inc., Miami Beach, FL (US)
Filed by Terran Biosciences Inc., New York, NY (US)
Filed on Feb. 16, 2024, as Appl. No. 18/444,450.
Claims priority of provisional application 63/523,619, filed on Jun. 27, 2023.
Claims priority of provisional application 63/461,543, filed on Apr. 24, 2023.
Prior Publication US 2024/0368149 A1, Nov. 7, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 417/04 (2006.01)
CPC C07D 417/04 (2013.01) 42 Claims
 
1. A compound according to the following formula:

OG Complex Work Unit Chemistry
wherein:
R1 and R2 are independently selected from hydrogen and C1-6 alkyl;
R3 is —C(O)R5;
R5 is C1-14 alkyl; and
X− is a pharmaceutically acceptable counterion.