US 12,269,033 B2
Device for accommodating a fluid sample
Michael Taagaard, Brønshøj (DK); and Peter Frischauf, Brønshøj (DK)
Assigned to Radiometer Medical ApS, Brønshøj (DK)
Appl. No. 16/954,733
Filed by Radiometer Medical ApS, Brønshøj (DK)
PCT Filed Dec. 19, 2018, PCT No. PCT/EP2018/085726
§ 371(c)(1), (2) Date Jun. 17, 2020,
PCT Pub. No. WO2019/121841, PCT Pub. Date Jun. 27, 2019.
Claims priority of application No. PA 2017 00739 (DK), filed on Dec. 21, 2017.
Prior Publication US 2021/0162411 A1, Jun. 3, 2021
Int. Cl. B01L 3/00 (2006.01)
CPC B01L 3/502746 (2013.01) [B01L 2200/0684 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0858 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/161 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/049 (2013.01); B01L 2400/086 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A multiple-use device comprising:
(a) an inner wall surface defining an outer limit of a measuring chamber for accommodating a fluid sample; and
(b) one or more sensors located inside or outside the measuring chamber,
wherein the inner wall surface comprises:
a surface structure which is adapted to control a propagation of a flow front of the fluid sample in a direction (x) during moving of the fluid sample into the measuring chamber through an inlet, during passing of the fluid sample through the measuring chamber and during moving of the fluid sample out of the measuring chamber through an outlet, and
a first wall section and a second wall section, wherein the first wall section and the second wall section are discrete from each other, wherein the surface structure is positioned along the first wall section and the second wall section,
wherein the surface structure comprises at least one surface structure element having a wavelike shape selected from semi-circular, semi-ellipsoidal, triangular, parallelogram, rectangular, square, any fusions thereof, and any combinations thereof, wherein the at least one surface structure element is configured to reduce a formation of trapped air in the fluid sample,
wherein the surface structure is selected depending on a flow speed of the flow front of the fluid sample, wherein the flow speed is applied by a difference in pressure between the inlet and the outlet of the measuring chamber and wherein the surface structure is adapted to increase capillary forces of the fluid sample along the surface structure, such that the fluid sample progresses in small steps in the direction (x) of the fluid propagation in the area of the surface structure, and
wherein the measuring chamber has a width, including end points, of from 1 to 5 mm, and wherein the measuring chamber is configured for use with one or more of the one or more sensors located inside or outside the measuring chamber.