US 12,268,901 B2
Targeting cell tropism receptors to inhibit cytomegalovirus infection
Timothy F. Kowalik, Princeton, MA (US); Xiaofei E, Westborough, MA (US); and Abraham L Brass, Newton, MA (US)
Assigned to University of Massachusetts, Westborough, MA (US)
Filed by UNIVERSITY OF MASSACHUSETTS, Boston, MA (US)
Filed on Sep. 20, 2022, as Appl. No. 17/933,709.
Application 17/933,709 is a division of application No. 16/604,735, granted, now 11,484,570, previously published as PCT/US2018/027469, filed on Apr. 13, 2018.
Claims priority of provisional application 62/485,742, filed on Apr. 14, 2017.
Prior Publication US 2023/0034732 A1, Feb. 2, 2023
Int. Cl. A61K 31/52 (2006.01); A61K 38/17 (2006.01); A61P 31/12 (2006.01); C07K 16/08 (2006.01); C07K 16/28 (2006.01); C12N 15/113 (2010.01)
CPC A61K 31/52 (2013.01) [A61K 38/177 (2013.01); A61P 31/12 (2018.01); C07K 16/089 (2023.08); C07K 16/28 (2013.01); C12N 15/1138 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01)] 5 Claims
 
1. A composition comprising an inhibitor of Olfactory Receptor Family 14 Subfamily 1 Member 1 (OR14I1), wherein the inhibitor of OR14I1 is a N-terminal peptide of OR14I1 comprising the amino acid sequence MDNLTKVTEFLLMEFSGIWELQVLHA (SEQ ID NO:1), or an active fragment thereof, and a pharmaceutically acceptable carrier.