US 12,268,866 B2
Systems and methods for implantable electrodes with feedback for application of electric field therapy within the body
Benjamin Hendricks, San Francisco, CA (US)
Assigned to Dignity Health, San Francisco, CA (US)
Appl. No. 18/551,765
Filed by Dignity Health, San Francisco, CA (US)
PCT Filed Apr. 11, 2022, PCT No. PCT/US2022/024265
§ 371(c)(1), (2) Date Sep. 21, 2023,
PCT Pub. No. WO2022/217144, PCT Pub. Date Oct. 13, 2022.
Claims priority of provisional application 63/173,410, filed on Apr. 10, 2021.
Prior Publication US 2024/0091525 A1, Mar. 21, 2024
Int. Cl. A61N 1/05 (2006.01); A61N 1/372 (2006.01); A61N 1/378 (2006.01)
CPC A61N 1/05 (2013.01) [A61N 1/37247 (2013.01); A61N 1/37252 (2013.01); A61N 1/3785 (2013.01)] 24 Claims
OG exemplary drawing
 
1. A system, comprising:
an implantable electrode comprising a plurality of contacts and configured to apply a stimulating waveform to a target structure and receive a measured voltage from the target structure; and
a processor in electrical communication with the plurality of contacts and a memory, the memory including instructions, which, when executed, cause the processor to:
execute, by the processor, a planning module that assigns a stimulating role or a measuring role to a contact of the plurality of contacts of the implantable electrode based on a tumor region present within the target structure;
apply, by a waveform generator in electrical communication with the processor, the stimulating waveform according to one or more waveform parameters, the one or more waveform parameters being based on one or more anticipated tissue parameters associated with a structure selection indicative of the target structure and based on the tumor region present within the target structure; and
adjust, at the processor, an electric field magnitude throughout the target structure based on the measured value that is resultant of the stimulating waveform from the target structure.