	US 12,268,798 B2
	Method for screening of unpleasant odor masking agents
Masato Murai, Kanagawa (JP); and Ikuo Terada, Kanagawa (JP)
Assigned to Takasago International Corporation, Tokyo (JP)
Filed by Takasago International Corporation, Tokyo (JP)
Filed on Jul. 27, 2021, as Appl. No. 17/443,737.
Claims priority of application No. 2020-127591 (JP), filed on Jul. 28, 2020; and application No. 2020-174788 (JP), filed on Oct. 16, 2020.
Prior Publication US 2022/0034866 A1, Feb. 3, 2022
Int. Cl. G01N 33/50 (2006.01); A61L 9/01 (2006.01); C12Q 1/66 (2006.01)

CPC A61L 9/01 (2013.01) [G01N 33/502 (2013.01); A61L 2209/21 (2013.01); C12Q 1/66 (2013.01); G01N 2333/705 (2013.01)]

4 Claims

1. A method for screening an unpleasant odor masking agent, comprising the steps of:

adding a test substance and an unpleasant odor-causing substance to olfactory receptor OR2L3 (SEQ ID NO: 2);

measuring a response of OR2L3 to the unpleasant odor-causing substance; and

identifying the test substance that suppresses the response of OR2L3 as a candidate substance for the unpleasant odor masking agent based on the measured response,

wherein the unpleasant odor is fecal odor, breath odor, dairy product-derived deterioration odor or citrus-derived deterioration odor.