	US 12,268,795 B2
	Zirconium and titanium phosphate coatings for implants and other substrates
Per Kjellin, Mölndal (SE); Fredrik Currie, Mölndal (SE); Paul Handa, Mölndal (SE); and Line Vikingsson, Mölndal (SE)
Assigned to Promimic AB, Mölndal (SE)
Appl. No. 16/967,047
Filed by Promimic AB, Mölndal (SE)
PCT Filed Feb. 8, 2019, PCT No. PCT/EP2019/053200 § 371(c)(1), (2) Date Aug. 3, 2020, PCT Pub. No. WO2019/155021, PCT Pub. Date Aug. 15, 2019.
Claims priority of application No. 1802184 (GB), filed on Feb. 9, 2018.
Prior Publication US 2021/0030921 A1, Feb. 4, 2021
Int. Cl. A61K 9/16 (2006.01); A61L 27/04 (2006.01); A61L 27/06 (2006.01); A61L 27/32 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01)

CPC A61L 27/32 (2013.01) [A61L 27/047 (2013.01); A61L 27/06 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 2300/406 (2013.01); A61L 2400/12 (2013.01); A61L 2420/06 (2013.01); A61L 2420/08 (2013.01); A61L 2430/02 (2013.01); A61L 2430/12 (2013.01); A61L 2430/24 (2013.01); A61L 2430/38 (2013.01)]

27 Claims

1. A substrate comprising a first coating on a surface thereof, the first coating comprising amorphous nanosized titanium phosphate particles, amorphous nanosized zirconium phosphate particles, or a mixture thereof, wherein the first coating has a thickness of from about 1 to about 1000 nm,

wherein the amorphous nanosized titanium phosphate particles and/or the amorphous nanosized zirconium phosphate particles in the first coating have a specific surface area of from about 5 m²/g to about 400 m²/g.