US 12,268,689 B2
Eutectic form A of Elagolix and pyrimethamine, preparation method therefor and use thereof
Guobin Ren, Shenzhen (CN); Weijie Ji, Shenzhen (CN); Dongxu Yi, Shenzhen (CN); and Jiajun Huang, Shenzhen (CN)
Assigned to SHENZHEN JINGTAI TECHNOLOGY CO., LTD, Guangdong (CN)
Filed by Shenzhen Rentai Pharmatech Ltd., Shenzhen (CN)
Filed on Jan. 27, 2022, as Appl. No. 17/586,160.
Application 17/586,160 is a continuation of application No. PCT/CN2019/098642, filed on Jul. 31, 2019.
Prior Publication US 2022/0143019 A1, May 12, 2022
Int. Cl. A61K 31/513 (2006.01); A61K 31/505 (2006.01)
CPC A61K 31/513 (2013.01) [A61K 31/505 (2013.01)] 18 Claims
 
1. An eutectic form A of Elagolix and pyrimethamine, wherein an X-ray powder diffraction of the eutectic form A using Cu-Kα radiation has characteristic peaks at 2θ angles of 8.1±0.2°, 12.2±0.2°, 13.3±0.2° and 21.1±0.2°.