US 12,268,676 B2
Antiviral applications of picolinic acid and its derivatives
Shashank Tripathi, Bengaluru (IN); Rohan Narayan, Bengaluru (IN); Abhijith Biji, Bengaluru (IN); and R. S. Rajmani, Bangalore (IN)
Assigned to Indian Institute of Science, Karnataka (IN)
Filed by INDIAN INSTITUTE OF SCIENCE, Karnataka (IN)
Filed on Jan. 19, 2022, as Appl. No. 17/578,968.
Claims priority of provisional application 63/139,696, filed on Jan. 20, 2021.
Prior Publication US 2022/0226292 A1, Jul. 21, 2022
Int. Cl. A61K 31/4402 (2006.01); A61P 31/16 (2006.01)
CPC A61K 31/4402 (2013.01) [A61P 31/16 (2018.01)] 16 Claims
 
1. A method for inhibiting entry of a virus into an uninfected host cell in a host, comprising treating the host with picolinic acid or a salt or derivative thereof, wherein said treating inhibits entry of the virus into the uninfected host cell by blocking viral and cellular membrane fusion.