US 12,268,594 B2
Split-type precisely anchored interventional mitral valve system
Lei Jin, Beijing (CN); Yingqiang Guo, Beijing (CN); Jia Wu, Beijing (CN); Liyan Li, Beijing (CN); Hong Mu, Beijing (CN); Kangjian Wu, Beijing (CN); and Zhihao Fan, Beijing (CN)
Assigned to BEIJING BALANCE MEDICAL TECHNOLOGY CO., LTD., Beijing (CN); and WEST CHINA HOSPITAL OF SICHUAN UNIVERSITY, Chengdu (CN)
Appl. No. 18/710,524
Filed by BEIJING BALANCE MEDICAL TECHNOLOGY CO., LTD., Beijing (CN); and WEST CHINA HOSPITAL OF SICHUAN UNIVERSITY, Chengdu (CN)
PCT Filed Nov. 17, 2022, PCT No. PCT/CN2022/132578
§ 371(c)(1), (2) Date May 15, 2024,
PCT Pub. No. WO2023/088369, PCT Pub. Date May 25, 2023.
Claims priority of application No. 202111361271.6 (CN), filed on Nov. 17, 2021.
Prior Publication US 2025/0009500 A1, Jan. 9, 2025
Int. Cl. A61F 2/24 (2006.01)
CPC A61F 2/2415 (2013.01) [A61F 2/2418 (2013.01); A61F 2/2433 (2013.01); A61F 2210/0014 (2013.01); A61F 2210/0076 (2013.01); A61F 2220/0008 (2013.01); A61F 2220/0083 (2013.01); A61F 2230/0093 (2013.01); A61F 2240/004 (2013.01)] 29 Claims
OG exemplary drawing
 
1. A split type precisely-anchorable transcatheter mitral valve system, characterized in that,
the system comprises a split transcatheter mitral valve anchoring stent and a transcatheter artificial biological mitral valve,
wherein the shape and structure of the transcatheter mitral valve anchoring stent are matched with the mitral valve real structure after patient image data is subjected to three-dimensional reconstruction, the transcatheter mitral valve anchoring stent is firstly delivered to the mitral valve position of the patient to be released, deformed, personalized and precisely aligned with the personalized precise alignment of the supravalvular and subvalvular tissues on the mitral valve position of the patient;
the transcatheter artificial biological mitral valve is delivered into the transcatheter mitral valve anchoring stent to be released, the transcatheter artificial biological mitral valve is released and deformed and expanded to a functional state, the transcatheter mitral valve anchoring stent is deformed again and combined with the expanded transcatheter artificial biological mitral valve, and meanwhile, the re-deformation of the transcatheter mitral valve anchoring stent causes the transcatheter mitral valve anchoring stent to be anchored with the subvalvular tissue in a preset combination;
the transcatheter mitral valve anchoring stent is an umbrella tubular stent structure, comprising an atrial surface, a ventricular surface and an anchoring stent connecting part therebetween, wherein the atrial surface is an umbrella sheet, and has an umbrella shape matching with a real personalized morphology of the three-dimensional reconstruction of the patient image data of the atrial surface of the patient, that is the first lattice portion; the ventricular surface comprises two positioning hook loops which are precisely preset with the boundary positions of the anterior and posterior leaflets of the mitral valve of the patient; the anchoring stent connecting part is funnel-shaped with a round opening, the diameter of the funnel opening is matched with the patient's mitral valve perivalvular inner diameter, and the opening of the lower end of the funnel is a second lattice portion that matches the morphology and degree of the mitral valve stenosis and/or regurgitation lesion.