US 12,268,511 B2
Methods and devices for providing a parameter that indicates a higher likelihood of a postoperative delirium occurring
Susanne Koch, Berlin (DE); and Claudia Spies, Berlin (DE)
Assigned to COVIDIEN LP, Mansfield, MA (US)
Filed by Covidien LP, Boulder, CO (US)
Filed on Jun. 5, 2024, as Appl. No. 18/734,876.
Application 18/734,876 is a continuation of application No. 17/252,113, granted, now 12,029,571, previously published as PCT/EP2019/065832, filed on Jun. 17, 2019.
Claims priority of application No. 102018114364.8 (DE), filed on Jun. 15, 2018.
Prior Publication US 2024/0315635 A1, Sep. 26, 2024
Int. Cl. A61B 5/374 (2021.01); A61B 5/00 (2006.01); G01R 23/15 (2006.01); G16H 10/60 (2018.01); G16H 50/20 (2018.01); G16H 50/70 (2018.01)
CPC A61B 5/374 (2021.01) [A61B 5/7271 (2013.01); G16H 10/60 (2018.01); G16H 50/70 (2018.01); G01R 23/15 (2013.01); G16H 50/20 (2018.01)] 15 Claims
OG exemplary drawing
 
1. A method for providing a parameter that indicates a heightened likelihood of postoperative delirium occurring, wherein the method comprises:
receiving at least one electroencephalography (EEG) signal from a patient over a period of time;
filtering the at least one EEG signal to produce at least one filtered EEG signal comprising a range of frequencies below a predefined frequency threshold;
determining a plurality of average amplitudes of the at least one filtered EEG signal over the period of time, wherein the plurality of average amplitudes comprises a first average amplitude at a first point in time within the period of time prior to an anesthesia-inducing loss of consciousness of the patient and a second average amplitude at a second point in time within the period of time when the patient enters the anesthesia-inducing loss of consciousness;
determining a difference value between the first average amplitude and the second average amplitude; and
providing the parameter that indicates the heightened likelihood of postoperative delirium occurring based on the difference value being greater than a predefined value.