US 11,946,926 B2
Method and apparatus for testing a biological sample
Emmanuel Guignet, Cressier (CH); and Stephane Bombard, Cressier (CH)
Assigned to Bio-Rad Europe GmbH, Basel (CH)
Appl. No. 16/955,014
Filed by BIO-RAD EUROPE GMBH, Basel (CH)
PCT Filed Dec. 18, 2018, PCT No. PCT/EP2018/085468
§ 371(c)(1), (2) Date Jun. 17, 2020,
PCT Pub. No. WO2019/121665, PCT Pub. Date Jun. 27, 2019.
Claims priority of application No. 17208591 (EP), filed on Dec. 19, 2017.
Prior Publication US 2020/0378947 A1, Dec. 3, 2020
Int. Cl. G01N 33/49 (2006.01); B01L 9/06 (2006.01); G01N 1/38 (2006.01); G01N 15/04 (2006.01); G01N 15/05 (2006.01); G01N 35/00 (2006.01)
CPC G01N 33/491 (2013.01) [B01L 9/06 (2013.01); G01N 1/38 (2013.01); G01N 15/042 (2013.01); G01N 15/05 (2013.01); G01N 35/00029 (2013.01); B01L 2200/025 (2013.01); B01L 2300/0627 (2013.01); G01N 2015/047 (2013.01); G01N 2035/00148 (2013.01); G01N 2035/00495 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A method of testing a biological sample, the method comprising:
providing a centrifuge comprising a rotor comprising one or more arms;
providing a centrifuge sample holder comprising an axis for hingedly coupling the centrifuge sample holder to an arm of the one or more arms of the rotor, a recess extending in a vertical direction when the centrifuge is not rotating, and a camera directly attached to an external surface of a wall of the centrifuge sample holder surrounding the recess;
arranging a transparent container comprising a test medium in the recess of said centrifuge sample holder such that the container has a fixed relationship with the camera directly attached to the centrifuge sample holder, wherein the camera is arranged at a location on the external surface of the centrifuge sample holder to image a portion of the container comprising said test medium;
arranging said biological sample in a location of said container above and not in contact with said test medium in said container in vertical orientation when the centrifuge is not rotating; and
with the camera, imaging a mixing of said biological sample with said test medium while centrifuging the sample holder.