US 11,946,868 B2
Concentration gradient fluorescence calibration sheet for laser microarray chip scanner and calibration method
Shuang An, Sichuan (CN); Guanbin Zhang, Sichuan (CN); Dong Liang, Sichuan (CN); and Shuying Zhao, Sichuan (CN)
Assigned to CHENGDU CAPITALBIO MEDIAB LTD, Sichuan (CN); and MIANYANG PEOPLE'S HOSPITAL, Sichuan (CN)
Appl. No. 17/595,036
Filed by CHENGDU CAPITALBIO MEDIAB LTD., Sichuan (CN); and MIANYANG PEOPLE'S HOSPITAL, Sichuan (CN)
PCT Filed Apr. 23, 2020, PCT No. PCT/CN2020/086375
§ 371(c)(1), (2) Date Nov. 5, 2021,
PCT Pub. No. WO2021/098142, PCT Pub. Date May 27, 2021.
Claims priority of application No. 201911148674.5 (CN), filed on Nov. 21, 2019.
Prior Publication US 2022/0307982 A1, Sep. 29, 2022
Int. Cl. G01N 21/64 (2006.01)
CPC G01N 21/6456 (2013.01) [G01N 2021/6463 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A concentration gradient fluorescence calibration sheet for a laser microarray chip scanner, characterized in that the concentration gradient fluorescence calibration sheet comprises a glass substrate and an inorganic nano fluorescent liquid lattice disposed on a surface of the glass substrate;
the inorganic nano fluorescent liquid lattice comprises a plurality of inorganic nano fluorescent liquid sub-lattices; inorganic fluorescent mixed liquid droplets of each inorganic nano fluorescent liquid sub-lattice are arranged in A rows×B columns, a solution concentration of the same row of inorganic nano fluorescent liquid droplets in the inorganic nano fluorescent liquid sub-lattices is the same, and the solution concentrations of two adjacent rows of inorganic nano fluorescent liquid droplets increase or decrease gradiently in multiples, wherein A is 5-20, and B is 10-40.