US 11,946,032 B2
Fixed bed sampler and related methods
José Castillo, Brussels (BE); Bastien Mairesse, Uccle (BE); Alex Chatel, Brussels (BE); Sebastien Jean-Pierre Michel Rodriguez, Ecaussines-Lalaing (BE); and Alexandre VAnhaver, Braine-le-Chateau (BE)
Assigned to UNIVERCELLS TECHNOLOGIES S.A., Nivelles (BE)
Appl. No. 16/981,333
Filed by UNIVERCELLS TECHNOLOGIES S.A., Nivelles (BE)
PCT Filed Mar. 18, 2019, PCT No. PCT/EP2019/056732
§ 371(c)(1), (2) Date Sep. 16, 2020,
PCT Pub. No. WO2019/175442, PCT Pub. Date Sep. 19, 2019.
Claims priority of provisional application 62/728,405, filed on Sep. 7, 2018.
Claims priority of provisional application 62/644,014, filed on Mar. 16, 2018.
Claims priority of application No. 2018/5179 (BE), filed on Mar. 16, 2018.
Prior Publication US 2021/0009933 A1, Jan. 14, 2021
Int. Cl. C12M 1/12 (2006.01); C12M 1/26 (2006.01); C12M 3/00 (2006.01)
CPC C12M 25/18 (2013.01) [C12M 23/46 (2013.01); C12M 33/18 (2013.01)] 11 Claims
OG exemplary drawing
 
1. An apparatus for use with a cell culture system, comprising:
a structured fixed bed comprising a substrate material for achieving cell growth and cell immobilization, said structured fixed bed comprising a spiral configuration with at least two layers in direct contact with one another;
a removable sample portion comprising the substrate material, the removable sample portion being separate from the structured fixed bed;
wherein the removable sample portion is located at least partially between the at least two layers.