US 11,945,792 B2
Crystalline forms of 6-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)nicotinamide
Xiangyang Chen, Beijing (CN); Zuopeng Wang, Shanghai (CN); and Liqin Yu, Nanjing (CN)
Assigned to Beijing Innocare Pharma Tech Co., Ltd, Beijing (CN)
Filed by BEIJING INNOCARE PHARMA TECH CO., LTD., Beijing (CN)
Filed on Mar. 3, 2021, as Appl. No. 17/191,310.
Application 17/191,310 is a continuation of application No. PCT/CN2019/106433, filed on Sep. 18, 2019.
Claims priority of provisional application 62/732,994, filed on Sep. 18, 2018.
Prior Publication US 2021/0188801 A1, Jun. 24, 2021
Int. Cl. C07D 401/04 (2006.01); A61K 31/4545 (2006.01)
CPC C07D 401/04 (2013.01) [A61K 31/4545 (2013.01); C07B 2200/13 (2013.01)] 7 Claims
 
1. A crystalline form of 6-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)nicotinamide having X-ray diffraction peaks at 5.4°±0.2°, 8.4°±0.2°, 18.7°±0.2°, 19.1°±0.2°, 16.1°±0.2°, 21.9°±0.2°, and 10.1°±0.2° degrees 2θ, and wherein the most intense peak is at 5.4±0.2 degrees 2θ.