	US 11,944,659 B2
	Method for improving sarcopenia by using Phellinus linteus
Chin-Chu Chen, Taiwan (CN); I-Chen Li, Taiwan (CN); Tsung-Ju Li, Taiwan (CN); Ting-Yu Lu, Taiwan (CN); and Yen-Po Chen, Taiwan (CN)
Assigned to GRAPE KING BIO LTD, Taiwan (CN)
Filed by GRAPE KING BIO LTD, Taiwan (CN)
Filed on Oct. 12, 2021, as Appl. No. 17/499,261.
Claims priority of application No. 109136177 (TW), filed on Oct. 19, 2020.
Prior Publication US 2022/0118037 A1, Apr. 21, 2022
Int. Cl. A61K 36/07 (2006.01); A23K 50/50 (2016.01); A23L 31/00 (2016.01); A23L 33/10 (2016.01); A61P 21/06 (2006.01); B01D 11/02 (2006.01)

CPC A61K 36/07 (2013.01) [A23K 50/50 (2016.05); A23L 31/00 (2016.08); A23L 33/10 (2016.08); A61P 21/06 (2018.01); B01D 11/0288 (2013.01); A23V 2002/00 (2013.01); A61K 2236/11 (2013.01); A61K 2236/333 (2013.01); A61K 2236/37 (2013.01)]

8 Claims

1. A method for treating sarcopenia in a subject in need thereof, comprising:

administering a composition comprising an effective dose of an extract of a fermented product of Phellinus linteus and/or its derivative as an active ingredient to the subject, wherein the Phellinus linteus is deposited in National Institute of Technology and Evaluation (NITE), International Patent Organism Depositary (IPOD) on November, 12th, 2020 with an accession number of NITE BP-03321, the extract comprises a water extract and/or an ethanol extract, the water extract is obtained by performing a water extraction step at 90° C. to 100° C. on the fermented product for 20 minutes to 40 minutes, and the ethanol extract is obtained by performing an ethanol extraction step at 10° C. to 40° C. on the fermented product for 40 minutes to 80 minutes combining with an ultrasonic oscillation with an ultrasound of 500 W to 700 W, 30 kHz to 50 kHz.