CPC A61K 31/397 (2013.01) [A61K 9/2018 (2013.01); A61K 31/138 (2013.01); A61K 45/06 (2013.01); A61P 37/00 (2018.01)] | 43 Claims |
1. A method of treating an autoimmune disease in a patient comprising
a) administering to said patient an initial titration regimen of siponimod;
b) administering to said patient 1-15 mg siponimod daily as a maintenance regimen; and
c) introducing in said patient a beta-blocker treatment the earliest at the first day when said patient is receiving the dosage of the maintenance regimen;
wherein said initial titration regimen comprises administering siponimod at a dosage lower than the dosage of the maintenance regimen and then increasing the dosage stepwise up to the dosage of the maintenance regimen.
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