US 12,266,439 B2
Therapeutic intervention methods, devices, and systems
Ravindra Mehta, La Jolla, CA (US)
Assigned to The Regents of the University of California, Oakland, CA (US)
Appl. No. 16/485,103
Filed by THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US)
PCT Filed Feb. 9, 2018, PCT No. PCT/US2018/017675
§ 371(c)(1), (2) Date Aug. 9, 2019,
PCT Pub. No. WO2018/148581, PCT Pub. Date Aug. 16, 2018.
Claims priority of provisional application 62/457,688, filed on Feb. 10, 2017.
Prior Publication US 2020/0043592 A1, Feb. 6, 2020
Int. Cl. G16H 20/40 (2018.01); A61M 1/16 (2006.01); A61M 1/34 (2006.01); A61M 1/36 (2006.01); A61M 16/00 (2006.01); A61M 60/139 (2021.01); A61M 60/148 (2021.01); A61M 60/178 (2021.01); A61M 60/216 (2021.01); A61M 60/295 (2021.01); A61M 60/515 (2021.01); A61M 60/531 (2021.01); G16H 15/00 (2018.01)
CPC G16H 20/40 (2018.01) [A61M 1/1603 (2014.02); A61M 1/3403 (2014.02); A61M 1/3689 (2014.02); A61M 16/024 (2017.08); A61M 60/139 (2021.01); A61M 60/148 (2021.01); A61M 60/178 (2021.01); A61M 60/216 (2021.01); A61M 60/295 (2021.01); A61M 60/515 (2021.01); A61M 60/531 (2021.01); G16H 15/00 (2018.01); A61M 1/1698 (2013.01); A61M 2210/0693 (2013.01); A61M 2210/1071 (2013.01); A61M 2210/1082 (2013.01); A61M 2210/125 (2013.01); A61M 2230/04 (2013.01); A61M 2230/208 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A method of treating a patient, the method comprising:
obtaining, in a processor, a plurality of measurements comprising demand parameters and capacity parameters that are related to a plurality of organs of the patient;
determining, via the processor, (i) an organ demand score for each of the plurality of organs based on demand parameters that reflect the demand placed by each organ on the remaining organs and (ii) an organ capacity score specific to each of the plurality of organs based on capacity parameters comprising functional elements required for homeostasis of each organ;
identifying an organ at risk of failure from the plurality of organs based on a mismatch between the organ demand score for the organ at risk and the organ capacity score for the organ at risk by calculating, via the processor, a demand-capacity probability score;
causing, via the processor, information to be displayed on a display screen that is indicative that the patient has organ failure and needs intervention when the demand-capacity probability score of the organ at risk is in a target range; and
providing for, via the processor, an administration of organ support to the organ at risk in the patient.