US 12,265,087 B2
Olfactory receptor as microglia marker and use thereof
Jae Hyung Koo, Daegu (KR); Na Hye Lee, Daegu (KR); and Yoon Gyu Jae, Daegu (KR)
Assigned to DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY, Daegu (KR)
Appl. No. 17/622,546
Filed by DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY, Daegu (KR)
PCT Filed Jun. 26, 2020, PCT No. PCT/KR2020/008344
§ 371(c)(1), (2) Date Dec. 23, 2021,
PCT Pub. No. WO2020/263011, PCT Pub. Date Dec. 30, 2020.
Claims priority of application No. 10-2019-0077256 (KR), filed on Jun. 27, 2019.
Prior Publication US 2022/0357342 A1, Nov. 10, 2022
Int. Cl. A61K 31/341 (2006.01); A61P 25/00 (2006.01); G01N 33/569 (2006.01); G01N 33/68 (2006.01)
CPC G01N 33/6872 (2013.01) [A61K 31/341 (2013.01); A61P 25/00 (2018.01); G01N 33/569 (2013.01)] 5 Claims
 
1. A method of preventing or treating a neuroinflammatory disease or meningitis, comprising:
administering a pharmaceutical composition comprising an inhibitor against the interaction between 2-pentylfuran and an odorant receptor, which is odorant receptor 110 (Olfr110) or odorant receptor 111 (Olfr111), as an active ingredient, to a subject in need thereof.