US 12,265,050 B2
Porous nanostructured electrodes for detection of neurotransmitters
Qing Cao, Yorktown Heights, NY (US); Hariklia Deligianni, Alpine, NJ (US); and Fei Liu, Yorktown Heights, NY (US)
Assigned to INTERNATIONAL BUSINESS MACHINES CORPORATION, Armonk, NY (US)
Filed by International Business Machines Corporation, Armonk, NY (US)
Filed on Apr. 25, 2023, as Appl. No. 18/306,265.
Application 18/306,265 is a division of application No. 16/684,888, filed on Nov. 15, 2019, granted, now 11,674,922.
Application 16/684,888 is a division of application No. 15/626,363, filed on Jun. 19, 2017, granted, now 10,900,924, issued on Jan. 26, 2021.
Prior Publication US 2023/0258597 A1, Aug. 17, 2023
Int. Cl. G01N 27/327 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61B 5/1468 (2006.01); A61B 5/24 (2021.01); C23C 16/02 (2006.01); C23C 16/40 (2006.01); C23C 16/56 (2006.01); G01N 27/30 (2006.01); G01N 27/36 (2006.01); H05K 3/12 (2006.01)
CPC G01N 27/3277 (2013.01) [A61B 5/0031 (2013.01); A61B 5/14539 (2013.01); A61B 5/1468 (2013.01); A61B 5/24 (2021.01); A61B 5/4041 (2013.01); A61B 5/6868 (2013.01); C23C 16/0227 (2013.01); C23C 16/403 (2013.01); C23C 16/56 (2013.01); G01N 27/301 (2013.01); G01N 27/304 (2013.01); G01N 27/308 (2013.01); G01N 27/36 (2013.01); A61B 2562/0285 (2013.01); A61B 2562/125 (2013.01); G01N 27/302 (2013.01); G01N 27/3278 (2013.01); H05K 3/12 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A device comprising:
a glass layer over a trench comprising an ionic solution;
a polymer layer on a top surface of the glass layer;
a porous electrode on a surface of the polymer layer, the porous electrode configured to measure a current of a neurotransmitter oxidation;
a reference electrode separated from the glass layer by the ionic solution; and
a pH sensing electrode in contact with a bottom surface of the glass layer.