US 12,264,310 B1
Intracellular radiation microdosimetric detection structure and detection method
Xianghong Jia, Weihai (CN); Pengzhi He, Weihai (CN); Chenyao Han, Weihai (CN); Quanqi Shi, Weihai (CN); Xiaoli Wang, Weihai (CN); Xiaoyan Gao, Weihai (CN); Shuai Wang, Weihai (CN); Shucheng Shi, Weihai (CN); and Weiming Li, Weihai (CN)
Assigned to SHANDONG UNIVERSITY, Weihai (CN)
Filed by SHANDONG UNIVERSITY, Weihai (CN)
Filed on Nov. 18, 2024, as Appl. No. 18/950,326.
Claims priority of application No. 202311798429.5 (CN), filed on Dec. 26, 2023.
Int. Cl. G01T 1/02 (2006.01); C12M 1/34 (2006.01); C12M 1/42 (2006.01); C12N 15/01 (2006.01); G01T 7/00 (2006.01)
CPC C12N 15/01 (2013.01) [C12M 35/08 (2013.01); C12M 41/30 (2013.01); G01T 1/026 (2013.01); G01T 7/00 (2013.01)] 10 Claims
OG exemplary drawing
 
1. An intracellular radiation microdosimetric detection structure, comprising:
a first semiconductor detector unit, a first pixel array detector, a cellular microfluidic chip, a second pixel array detector, and a second semiconductor detector unit that are sequentially arranged in layers, wherein the cellular microfluidic chip is configured for cell fixation and culture;
the first semiconductor detector unit and the second semiconductor detector unit form a charged particle energy information detector combination for detecting deposit energy of charged particles in a semiconductor detector; and
the first pixel array detector and the second pixel array detector form a charged particle flux and position information detector combination for measuring a flux and an angle of charged particles incident at a position of the cellular microfluidic chip.