or a pharmaceutically acceptable salt thereof;

wherein:

Ring A is selected from C_3-6cycloalkyl or C_6-10aryl;

R¹ is selected from H, C_1-6alkyl, C_1-6heteroalkyl, C_1-6haloalkyl, C_3-6cycloalkyl, 3- to 10-membered heterocycloalkyl, C_6-10aryl, 6- to 10-membered heteroaryl; wherein each alkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl is independently optionally substituted with one or more substituents selected from oxo, halo, —OR¹⁸, C_1-4alkyl, C_1-4alkoxy, C_1-4heteroalkyl, C_1-4haloalkyl, —CN, and NR²⁰R²¹,

R² is selected from halo, —CN, —OH, —OMe, —OEt, —NH₂, —NHMe, —NMe₂, Me, Et, n-Pr, i-Pr, —CF₃, and cyclopropyl;

R³ is selected from H, halo, —CN, —OR¹⁸, —SOR¹⁵, —NR¹⁶R¹⁷, —C(O)NR¹⁶R¹⁷, —SO₂NR¹⁶R¹⁷, —C(O)R¹⁸, —C(O)OR¹⁸, —NR¹⁹C(O)R¹⁸, —NR¹⁹C(O)NR¹⁶R¹⁷, —NR¹⁹SO₂R¹⁵, —NR¹⁹SO₂NR¹⁶R¹⁷, C_1-6alkyl, C_2-6alkenyl, C_2-6alkynyl, C_1-6heteroalkyl, C_1-6haloalkyl, C_3-6cycloalkyl, 3- to 10-membered heterocycloalkyl, C_6-10aryl, and 6- to 10-membered heteroaryl; wherein each alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl is independently optionally substituted with one or more substituents selected from oxo, halo, —OR¹⁸, C_1-4alkyl, C_1-4alkoxy, C_1-4heteroalkyl, C_1-4haloalkyl, —CN, and —NR²⁰R²¹;

R⁴ is selected from C_1-6alkyl, C_2-6heteroalkyl, C_1-6haloalkyl, C_3-6cycloalkyl, 3- to 10-membered heterocycloalkyl, C_6-10aryl, 6- to 10-membered heteroaryl, —O(C_0-4alkyl)C_3-6cycloalkyl, —O(C_0-4alkyl)(3- to 10-membered heterocycloalkyl), —O(C_0-4alkyl)C_6-10aryl, —O(C_0-4alkyl)(6- to 10-membered heteroaryl), —O(C_0-4alkyl)C(O)OR¹⁸, —O(C_0-4alkyl)C(O)NR¹⁹SO₂R¹⁵, —O(C_0-4alkyl)SO₂NR¹⁹C(O)R¹⁸, —O(C_3-6cycloalkyl)C_3-6cycloalkyl, —O(C_3-6cycloalkyl)(3- to 10-membered heterocycloalkyl), —O(C_3-6cycloalkyl)C_6-10aryl, —O(C_3-6cycloalkyl)(6- to 10-membered heteroaryl), —O(C_3-6cycloalkyl)C(O)OR¹⁸, —(C_1-4alkyl)C_3-6cycloalkyl, —(C_1-4alkyl)(3 to 10-membered heterocycloalkyl), —(C_1-4alkyl)C_6-10aryl, —(C_1-4alkyl)(6- to 10-membered heteroaryl), and —(C_1-4alkyl)C(O)OR¹⁸; wherein each alkyl, heteroalkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl is independently optionally substituted with one or more substituents selected from C_1-4alkyl, oxo, halo, —OR¹⁸, —CN, —NR¹⁶R¹⁷, —C(O)NR¹⁶R¹⁷, —SO₂NR¹⁶R¹⁷, —C(O)R¹⁸, —C(O)OR¹⁸, —(C_1-4alkyl)OC(O)(C_1-4alkyl), —(C_1-4alkyl)OC(O)OR¹⁸, —NR¹⁹C(O)R¹⁸, —NR¹⁹C(O)NR¹⁶R¹⁷, —NR¹⁹SO₂R¹⁵, and —NR¹⁹SO₂NR¹⁶R¹⁷; and

R⁴′ and R⁴″ are each independently selected from H, C_1-6alkyl, C_2-6heteroalkyl, C_1-6haloalkyl, C_3-6cycloalkyl, 3- to 10-membered heterocycloalkyl, C_6-10aryl, 6- to 10-membered heteroaryl, —O(C_0-4alkyl)C_3-6cycloalkyl, —O(C_0-4alkyl)(3- to 10-membered heterocycloalkyl), —O(C_0-4alkyl)C_6-10aryl, —O(C_0-4alkyl)(6- to 10-membered heteroaryl), —O(C_0-4alkyl)C(O)OR¹⁸, —O(C_0-4alkyl)C(O)NR¹⁹SO₂R¹⁵, —O(C_0-4alkyl)SO₂NR¹⁹C(O)R¹⁸, —O(C_3-6cycloalkyl)C_3-6cycloalkyl, —O(C_3-6cycloalkyl)(3- to 10-membered heterocycloalkyl), —O(C_3-6cycloalkyl)C_6-10aryl, —O(C_3-6cycloalkyl)(6- to 10-membered heteroaryl), —O(C_3-6cycloalkyl)C(O)OR¹⁸, —(C_1-4alkyl)C_3-6cycloalkyl, —(C_1-4alkyl)(3- to 10-membered heterocycloalkyl), —(C_1-4alkyl)C_6-10aryl, and —(C_1-4alkyl)(6- to 10-membered heteroaryl); wherein each alkyl, heteroalkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl is independently optionally substituted with one or more substituents selected from oxo, halo, —OR¹⁸, —CN, —NR¹⁶R¹⁷, —C(O)NR¹⁶R¹⁷, —SO₂NR¹⁶R¹⁷, —C(O)R¹⁸, —C(O)OR¹⁸, —(C_1-4alkyl)OC(O)(C_1-4alkyl), —(C_1-4alkyl)OC(O)OR¹⁸, —NR¹⁹C(O)R¹⁸, —NR¹⁹C(O)NR¹⁶R¹⁷, —NR¹⁹SO₂R¹⁵, and —NR¹⁹SO₂NR¹⁶R¹⁷; or

R³ is H; and R⁴, R⁴′, and R⁴″ are taken together, along with the carbon atom to which they are attached, to form —C(O)R¹⁸ or 6- to 10-membered heteroaryl;

R⁵ is selected from H, C_1-6alkyl, C_1-6heteroalkyl, C_1-6haloalkyl, C_3-6cycloalkyl, 3- to 10-membered heterocycloalkyl, C_6-10aryl, and 6- to 10-membered heteroaryl; wherein each alkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl is independently optionally substituted with one or more substituents selected from oxo, halo, —OR¹⁸, C_1-4alkyl, C_1-4alkoxy, C_1-4heteroalkyl, C_1-4haloalkyl, —CN, and NR²⁰R²¹;

R⁶ and R⁷ are each independently selected from H, C_1-6alkyl, C_1-6heteroalkyl, C_1-6haloalkyl, C_3-6cycloalkyl, 3- to 10-membered heterocycloalkyl, C_6-10aryl, 6- to 10-membered heteroaryl, —(C_1-4alkyl)C_3-6cycloalkyl, —(C_1-4alkyl)(3- to 10-membered heterocycloalkyl), —(C_1-4alkyl)C_6-10aryl, and —(C_1-4alkyl)(6- to 10-membered heteroaryl); wherein each alkyl, cycloalkyl, heterocycloalkyl, aryl, and heteroaryl is independently optionally substituted with one or more substituents selected from oxo, halo, —OR¹⁸, C_1-4alkyl, C_1-4alkoxy, C_1-4heteroalkyl, C_1-4haloalkyl, —CN, and —NR²⁰R²¹;

R⁸ and R⁹ are both H;

each R¹⁰ is independently selected from halo, —CN, —OR¹⁸, —NR¹⁶R¹⁷, —C(O)NR¹⁶R¹⁷, —SO₂NR¹⁶R¹⁷, —C(O)R¹⁸, —C(O)OR¹⁸, —NR¹⁹C(O)R¹⁸, C_1-6alkyl, C_1-6heteroalkyl, C_1-6haloalkyl, C_3-6cycloalkyl, 3- to 10-membered heterocycloalkyl; wherein each alkyl, cycloalkyl, and heterocycloalkyl is independently optionally substituted with one or more substituents selected from oxo, halo, —OR¹⁸, C_1-4alkyl, C_1-4alkoxy, C_1-4heteroalkyl, C_1-4haloalkyl, —CN, and —NR²⁰R²¹,

R¹¹, R¹², R¹³, and R¹⁴ are each independently selected from H, halo, —CN, —OR¹⁸, —NR¹⁶R¹⁷, —C(O)NR¹⁶R¹⁷, —SO₂NR¹⁶R¹⁷, —C(O)R¹⁸, —C(O)OR¹⁸, —NR¹⁹C(O)R¹⁸, C_1-6alkyl, and C_1-6haloalkyl;

each R¹⁵ is independently selected from C_1-4alkyl, C_1-4haloalkyl, C_3-6cycloalkyl, 3- to 10-membered heterocycloalkyl, C_6-10aryl, and 6- to 10-membered heteroaryl;

each R¹⁶ and R¹⁷ is independently selected from H, C_1-4alkyl, C_1-4heteroalkyl, C_1-4haloalkyl, C_3-6cycloalkyl, 3- to 10-membered heterocycloalkyl, C_6-10aryl, 6- to 10-membered heteroaryl; or

an R¹⁶ and an R¹⁷ may be taken together along with the nitrogen atom to which they are attached to form a 3- to 10-membered heterocycloalkyl;

each R¹⁸ is independently selected from H, C_1-4alkyl, C_1-4heteroalkyl, C_1-4haloalkyl, and C_3-6cycloalkyl;

each R¹⁹ is independently selected from H, C_1-4alkyl, C_1-4heteroalkyl, C_1-4haloalkyl, and C_3-6cycloalkyl; and

each R²⁰ and R²¹ is independently selected from H, C_1-4alkyl, C_1-4heteroalkyl, C_1-4haloalkyl, C_3-6cycloalkyl, 3- to 10-membered heterocycloalkyl, C_6-10aryl, 6- to 10-membered heteroaryl; or

an R²⁰ and an R²¹ may be taken together along with the nitrogen atom to which they are attached to form a 3- to 10-membered heterocycloalkyl; and

n is 0, 1, 2, 3, or 4.