US 12,264,142 B2
Heterocyclic compounds
Dan Florin Stoicescu, Aubonne (CH)
Assigned to FLORATEK PHARMA SA, Aubonne (CH)
Appl. No. 17/755,103
Filed by FLORATEK PHARMA SA, Aubonne (CH)
PCT Filed Oct. 21, 2020, PCT No. PCT/EP2020/079653
§ 371(c)(1), (2) Date Apr. 21, 2022,
PCT Pub. No. WO2021/078811, PCT Pub. Date Apr. 29, 2021.
Claims priority of application No. 1915191 (GB), filed on Oct. 21, 2019.
Prior Publication US 2022/0402889 A1, Dec. 22, 2022
Int. Cl. C07D 311/80 (2006.01); A61P 3/00 (2006.01); C07D 221/06 (2006.01); C07D 335/04 (2006.01)
CPC C07D 311/80 (2013.01) [C07D 221/06 (2013.01); C07D 335/04 (2013.01); A61P 3/00 (2018.01)] 7 Claims
 
1. A compound of formula (1):

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt or solvate thereof,
wherein:
Y, X1 and X2 are —O;
R1, R2, R3, R4, R5, and R6 are H; and
Z1 and Z2, independently, are NHR8; wherein
R8 is selected from methyl and propyl.