US 12,263,255 B2
Debriding wound dressing, process of manufacture and useful articles thereof
Mark E. Dillon, Center Valley, PA (US); Krishna Narayanan, Pittsburgh, PA (US); and Sean Michael Adams, Allentown, PA (US)
Assigned to Bio Med Sciences, Inc., Allentown, PA (US)
Filed by Mark E. Dillon, Center Valley, PA (US); Krishna Narayanan, Pittsburgh, PA (US); and Sean Michael Adams, Allentown, PA (US)
Filed on Dec. 12, 2018, as Appl. No. 16/218,197.
Claims priority of provisional application 62/597,798, filed on Dec. 12, 2017.
Prior Publication US 2019/0192724 A1, Jun. 27, 2019
Int. Cl. A61L 15/38 (2006.01); A61F 13/00 (2024.01); A61F 13/05 (2024.01); A61F 13/06 (2006.01); A61F 13/15 (2006.01); A61F 13/36 (2006.01); A61F 13/511 (2006.01); A61F 13/53 (2006.01); A61L 15/22 (2006.01); A61L 15/26 (2006.01); A61L 15/42 (2006.01); A61L 15/44 (2006.01)
CPC A61L 15/38 (2013.01) [A61F 13/00063 (2013.01); A61F 13/05 (2024.01); A61F 13/069 (2013.01); A61F 13/15699 (2013.01); A61F 13/36 (2013.01); A61F 13/51113 (2013.01); A61F 13/51121 (2013.01); A61L 15/225 (2013.01); A61L 15/26 (2013.01); A61L 15/425 (2013.01); A61L 15/44 (2013.01); A61F 2013/00089 (2013.01); A61F 2013/530226 (2013.01); A61F 2013/530802 (2013.01); A61L 2300/254 (2013.01); A61L 2300/40 (2013.01); A61L 2400/00 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A wound dressing for active continuous debridement of devitalized tissues in non-healing wounds, comprising
a substrate, the substrate having a non-adherent wound contacting layer having a wound contacting side, the non-adherent wound contacting layer comprising only silicone,
the wound dressing having a wound contacting surface, the wound contacting side of the non-adherent wound contacting layer comprising the entire wound contacting surface of the wound dressing, and
a coating of an effective amount of an enzymatic debriding agent on and being in direct contact with the wound contacting side of the non-adherent wound contacting layer,
the enzymatic debriding agent being collagenase, and
the collagenase being 90% pure collagenase, and the collagenase on the wound contacting side of the non-adherent wound contacting layer having a coating weight of 1.31 mg/square centimeter.