US 12,263,253 B2
Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof
Chase Spenser Coffman, Newton, MA (US); Lyndon Fitzgerald Charles, Jr., Medford, MA (US); Paul Brown, Boston, MA (US); Daniel Benjamin Dadon, East Boston, MA (US); Lisa Liu, Somerville, MA (US); Sadiqua Shadbar, Allston, MA (US); and Chaitanya Sudrik, Stoneham, MA (US)
Assigned to Elektrofi, Inc., Boston, MA (US)
Filed by Elektrofi, Inc., Boston, MA (US)
Filed on Aug. 27, 2024, as Appl. No. 18/816,200.
Application 18/816,200 is a continuation of application No. 17/058,339, granted, now 12,115,262, previously published as PCT/US2019/033875, filed on May 24, 2019.
Claims priority of provisional application 62/676,169, filed on May 24, 2018.
Prior Publication US 2024/0415782 A1, Dec. 19, 2024
Int. Cl. A61K 9/51 (2006.01); A61K 31/167 (2006.01); A61K 45/06 (2006.01); A61K 47/02 (2006.01); A61K 47/14 (2017.01); A61K 47/18 (2017.01); A61K 47/26 (2006.01)
CPC A61K 9/5192 (2013.01) [A61K 31/167 (2013.01); A61K 45/06 (2013.01); A61K 47/02 (2013.01); A61K 47/14 (2013.01); A61K 47/186 (2013.01); A61K 47/26 (2013.01)] 20 Claims
 
1. A composition comprising dehydrated particles, wherein the particles: comprise a protein having 0.5 to 1.0 activity per unit, are suspended in a non-aqueous liquid, and have less than 10% aggregation of the protein.