	US 12,263,251 B2
	Orally available articles containing at least one stabilized supplement therein
Timothy Brian Chiprich, Huntington Beach, CA (US); Argelia Sinay Melendez, Montebello, CA (US); Bibu Philip George, Norwalk, CA (US); David Wood, Yorba Linda, CA (US); Jangsoon Park, Cypress, CA (US); Jung Ku Cho, La Palma, CA (US); Lilyan Hong Tran, Fountain Valley, CA (US); Paul Hwang, Fullerton, CA (US); and Ronnie Bayless, Cerritos, CA (US)
Assigned to Captek Softgel International, Cerritos, CA (US)
Filed by Captek Softgel International, Cerritos, CA (US)
Filed on Dec. 29, 2023, as Appl. No. 18/400,346.
Application 18/400,346 is a division of application No. 16/141,070, filed on Sep. 25, 2018, granted, now 11,896,720.
Claims priority of provisional application 62/563,562, filed on Sep. 26, 2017.
Prior Publication US 2024/0130977 A1, Apr. 25, 2024
Int. Cl. A61K 9/50 (2006.01); A23G 1/00 (2006.01); A23K 10/18 (2016.01); A23K 20/10 (2016.01); A23K 20/174 (2016.01); A23K 50/20 (2016.01); A23K 50/30 (2016.01); A23K 50/40 (2016.01); A23K 50/50 (2016.01); A23K 50/70 (2016.01); A23L 29/206 (2016.01); A23L 33/105 (2016.01); A23L 33/135 (2016.01); A23P 10/30 (2016.01); A61K 9/00 (2006.01); A61K 9/48 (2006.01); A61K 31/715 (2006.01); A61K 47/36 (2006.01)

CPC A61K 9/5057 (2013.01) [A23G 1/00 (2013.01); A23K 10/18 (2016.05); A23K 20/10 (2016.05); A23K 20/174 (2016.05); A23K 50/20 (2016.05); A23K 50/30 (2016.05); A23K 50/40 (2016.05); A23K 50/50 (2016.05); A23K 50/70 (2016.05); A23L 33/105 (2016.08); A23L 33/135 (2016.08); A23P 10/30 (2016.08); A61K 9/0056 (2013.01); A61K 9/4808 (2013.01); A61K 9/4833 (2013.01); A61K 9/4858 (2013.01); A61K 9/4891 (2013.01); A23L 29/206 (2016.08); A61K 31/715 (2013.01); A61K 47/36 (2013.01)]

15 Claims

1. A method of making an orally available softgel, the method comprising:

pre-wetting a probiotic with an edible oil to produce a wetted supplement, wherein the edible oil is present in a range of 25% to 75% by weight of a total weight of the probiotic and edible oil;

heating the wetted supplement to a temperature in a range of 35° C. to 40° C.;

blending the wetted supplement and a molten chocolate component together to produce a liquid fill material;

encapsulating the liquid fill material in a softgel coating to produce an orally available softgel; and

cooling the orally available softgel to have a softgel capsule shell comprising 5% to 15% by weight water;

wherein the fill material is a solid at room temperature in the cooled orally available softgel.