US 12,263,242 B2
Container with particles for use with inhaler
Gerard Zuber, Boulens (CH); and Judith Waller, Ostersund (SE)
Assigned to Philip Morris Products S.A., Neuchâtel (CH)
Appl. No. 16/623,923
Filed by PHILIP MORRIS PRODUCTS S.A., Neuchâtel (CH)
PCT Filed Jun. 26, 2018, PCT No. PCT/IB2018/054720
§ 371(c)(1), (2) Date Dec. 18, 2019,
PCT Pub. No. WO2019/003118, PCT Pub. Date Jan. 3, 2019.
Claims priority of application No. 17178416 (EP), filed on Jun. 28, 2017.
Prior Publication US 2020/0196674 A1, Jun. 25, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A24F 40/42 (2020.01); A24B 15/16 (2020.01); A24B 15/40 (2006.01); A24F 40/20 (2020.01); A24F 42/20 (2020.01); A24F 42/60 (2020.01); A61K 9/00 (2006.01); A61M 15/00 (2006.01)
CPC A61K 9/0075 (2013.01) [A24B 15/16 (2013.01); A24B 15/403 (2013.01); A24F 40/20 (2020.01); A24F 40/42 (2020.01); A24F 42/20 (2020.01); A24F 42/60 (2020.01); A61M 15/003 (2014.02); A61M 15/0035 (2014.02); A61M 2202/064 (2013.01); A61M 2206/16 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A container containing a powder system comprising:
a first plurality of particles having a mass median aerodynamic diameter particle size of about 10 micrometers or less;
a second plurality of particles having a mass median aerodynamic diameter particle size of about 20 micrometers or greater;
wherein the powder system comprises a weight ratio of the first plurality of particles to second plurality of particles of about 1:1 to about 10:1, and
a single aperture extending through the container,
wherein the container is a capsule and the single aperture extends through a capsule endcap and the capsule comprises a longitudinal axis and the single aperture is incident with the longitudinal axis, and wherein the single aperture has a diameter of about 0.5 mm to about 1.5 mm, or an open surface area of the single aperture is in a range from about 0.1% to about 0.5% of the total surface area of the container, and wherein the container is configured to release at least 10 uniform fractional amounts of the powder system.