	US 12,263,208 B2
	Recombinant cell wall hydrolases
Teresa Shock, San Francisco, CA (US); Oliver Liu, San Francisco, CA (US); Maritza Miller, Oakland, CA (US); and Jennifer Shock, San Francisco, CA (US)
Assigned to Topaz Biosciences, Inc., Emeryville, CA (US)
Filed by Topaz Biosciences, Inc., Emeryville, CA (US)
Filed on Sep. 11, 2024, as Appl. No. 18/882,318.
Application 18/882,318 is a continuation of application No. PCT/US2024/034521, filed on Jun. 18, 2024.
Claims priority of provisional application 63/639,416, filed on Apr. 26, 2024.
Claims priority of provisional application 63/509,160, filed on Jun. 20, 2023.
Prior Publication US 2025/0000956 A1, Jan. 2, 2025
Int. Cl. A61K 38/48 (2006.01); A61K 9/06 (2006.01); A61P 17/00 (2006.01); C12N 9/50 (2006.01)

CPC A61K 38/482 (2013.01) [A61K 9/06 (2013.01); A61P 17/00 (2018.01); C12N 9/50 (2013.01)]

29 Claims

1. A recombinant cell wall hydrolase (CWH) comprising:

a) an enzymatically active domain (EAD) from LysSA12; and

b) a cell wall binding domain (CBD) from PlySs2.