US 12,263,192 B2
Compositions for management of disorders of the gastrointestinal tract
Mark Grabowsky, New York, NY (US); Raymond J. Playford, Cobham (GB); Timothy W. Starzl, Boulder, CO (US); Tania Marchbank, Epsom (GB); Paul Kelly, Phoenix, AZ (US); and Naheed Choudhry, Phoenix, AZ (US)
Assigned to PanTheryx, Inc., Phoenix, AZ (US)
Appl. No. 17/433,723
Filed by PanTheryx, Inc., Phoenix, AZ (US)
PCT Filed Feb. 26, 2020, PCT No. PCT/US2020/019923
§ 371(c)(1), (2) Date Aug. 25, 2021,
PCT Pub. No. WO2020/176637, PCT Pub. Date Sep. 3, 2020.
Claims priority of provisional application 62/978,104, filed on Feb. 18, 2020.
Claims priority of provisional application 62/940,133, filed on Nov. 25, 2019.
Claims priority of provisional application 62/896,429, filed on Sep. 5, 2019.
Claims priority of provisional application 62/810,637, filed on Feb. 26, 2019.
Prior Publication US 2022/0047646 A1, Feb. 17, 2022
Int. Cl. A61K 35/57 (2015.01); A61K 31/07 (2006.01); A61K 31/355 (2006.01); A61K 31/4415 (2006.01); A61K 31/51 (2006.01); A61K 31/593 (2006.01); A61K 31/714 (2006.01); A61K 33/04 (2006.01); A61K 33/18 (2006.01); A61K 33/34 (2006.01); A61K 33/42 (2006.01); A61K 35/20 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 39/40 (2006.01); A61K 39/42 (2006.01); A61P 1/00 (2006.01)
CPC A61K 35/57 (2013.01) [A61K 31/07 (2013.01); A61K 31/355 (2013.01); A61K 31/4415 (2013.01); A61K 31/51 (2013.01); A61K 31/593 (2013.01); A61K 31/714 (2013.01); A61K 33/04 (2013.01); A61K 33/18 (2013.01); A61K 33/34 (2013.01); A61K 33/42 (2013.01); A61K 35/20 (2013.01); A61K 39/39583 (2013.01); A61K 39/40 (2013.01); A61K 39/42 (2013.01); A61P 1/00 (2018.01); A61K 2039/55 (2013.01)] 23 Claims
 
1. A method of treating small intestinal bacterial overgrowth (SIBO) in a subject in need thereof, the method comprising administering the subject an effective amount of a composition comprising:
a) an egg antibody product comprising at least one specific avian antibody or antigen binding fragment thereof, and
b) a bovine colostrum;
wherein the administration results in treatment of the SIBO.